ReviewGenetics2013
The molecular genetics of insecticide resistance.
Review in Genetics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 133 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
133 citing papers in PubMed.
- From bench to farm: leveragingFly · 2027Review
- Assessing the potential for insecticide cross-resistance to a novel insecticide in the Colorado potato beetle (Leptinotarsa decemlineata) using phenotypic and transcript expression analysis.Pest management science · 2026Article
- Insecticide resistance evolution and assisted gene flow interact to shape the evolution of plasticity.bioRxiv : the preprint server for biology · 2026Article
- Genotype by environmental interactions shape insecticide resistance phenotypes in Culex pipiens and Culex restuans.Heredity · 2026Article
- Article
- The diversity of insecticide target site mutations in Apis mellifera.BMC genomics · 2026Article
- Fitness costs of sublethal cyantraniliprole exposure: life-history trade-offs in the non-target insect Musca domestica.Scientific reports · 2026Article
- Monitoring of Insecticide Resistance and Resistance-Related Point Mutations in Field-CollectedInsects · 2026Article
- Metabolic resistance of the tiger mosquito to pyrethroid insecticides in La Réunion Island likely results from local adaptation.Genome biology and evolution · 2026Article
- Spatial and temporal signatures of genomic insecticide resistance in the Anopheles arabiensis mosquito malaria vector from Ethiopia.Research square · 2026Article
- Pyrethroid resistance in Aedes aegypti: genetic mechanisms worldwide, and recommendations for effective vector control.Parasites & vectors · 2025Review
- Review
- Recurrent mutations drive the rapid evolution of pesticide resistance in the two-spotted spider miteeLife · 2025Article
- Characterization of cyantraniliprole resistance in Spodoptera frugiperda: Selection, inheritance pattern, and cross-resistance to other diamide insecticides.Pest management science · 2025Article
- Microbiome evolution plays a secondary role in host rapid adaptation.bioRxiv : the preprint server for biology · 2025Article
- Precise lineage tracking using molecular barcodes demonstrates fitness trade-offs for ivermectin resistance in nematodes.G3 (Bethesda, Md.) · 2025Article
- Response of Amblyseius swirskii to deltamethrin.Pest management science · 2025Article
- The Genome of Lolium multiflorum Reveals the Genetic Architecture of Paraquat Resistance.Molecular ecology · 2025Article
- Copy number variation contributes to parallel local adaptation in an invasive plant.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Omics Approaches in Understanding Insecticide Resistance in Mosquito Vectors.International journal of molecular sciences · 2025Review
73 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
The past 60 years have seen a revolution in our understanding of the molecular genetics of insecticide resistance. While at first the field was split by arguments about the relative importance of mono- vs. polygenic resistance and field- vs. laboratory-based selection, the application of molecular cloning to insecticide targets and to the metabolic enzymes that degrade insecticides before they reach those targets has brought out an exponential growth in our understanding of the mutations involved. Molecular analysis has confirmed the relative importance of single major genes in target-site resistance and has also revealed some interesting surprises about the multi-gene families, such as cytochrome P450s, involved in metabolic resistance. Identification of the mutations involved in resistance has also led to parallel advances in our understanding of the enzymes and receptors involved, often with implications for the role of these receptors in humans. This Review seeks to provide an historical perspective on the impact of molecular biology on our understanding of resistance and to begin to look forward to the likely impact of rapid advances in both sequencing and genome-wide association analysis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.