ReviewNeuromolecular medicine2013
Protein sumoylation in brain development, neuronal morphology and spinogenesis.
Review in Neuromolecular medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 29 citations in OpenAlex.
- Fetal Neuronal Vesicles in the Assessment of Perinatal Brain Dysfunction and Late-Onset Growth Restriction: A Pilot Study.International journal of molecular sciences · 2026Article
- SUMO Regulation of Ion Channels in Health and Disease.Physiology (Bethesda, Md.) · 2025Review
- Non-Invasive Assessment of Neurogenesis Dysfunction in Fetuses with Early-Onset Growth Restriction Using Fetal Neuronal Exosomes Isolating from Maternal Blood: A Pilot Study.International journal of molecular sciences · 2025Article
- Review
- SENP5 deteriorates traumatic brain injury via SUMO2-dependent suppression of E2F1 SUMOylation.Acta biochimica et biophysica Sinica · 2023Article
- Impact of RSUME Actions on Biomolecular Modifications in Physio-Pathological Processes.Frontiers in endocrinology · 2022Review
- PDPK1 regulates autophagosome biogenesis by binding to PIK3C3.Autophagy · 2021Article
- Cask methylation involved in the injury of insulin secretion function caused by interleukin1-β.Journal of cellular and molecular medicine · 2020Article
- Post-translational modifications of the Fragile X Mental Retardation Protein in neuronal function and dysfunction.Molecular psychiatry · 2020Review
- Sumoylation regulates FMRP-mediated dendritic spine elimination and maturation.Nature communications · 2018Article
- Response: Commentary: Analysis of SUMO1-conjugation at synapses.Frontiers in cellular neuroscience · 2018Article
- Analysis of SUMO1-conjugation at synapses.eLife · 2017Article
- Comprehensive whole genome sequence analyses yields novel genetic and structural insights for Intellectual Disability.BMC genomics · 2017Article
- Commentary: Analysis of SUMO1-conjugation at synapses.Frontiers in cellular neuroscience · 2017Article
- The language-related transcription factor FOXP2 is post-translationally modified with small ubiquitin-like modifiers.Scientific reports · 2016Article
- Sumoylation in Synaptic Function and Dysfunction.Frontiers in synaptic neuroscience · 2016Review
- Tracking the activity-dependent diffusion of synaptic proteins using restricted photoconversion of Dendra2.Frontiers in cellular neuroscience · 2015Article
- SETX sumoylation: A link between DNA damage and RNA surveillance disrupted in AOA2.Rare diseases (Austin, Tex.) · 2014Article
- 19q13.11 microdeletion concomitant with ins(2;19)(p25.3;q13.1q13.4)dn in a boy: potential role of UBA2 in the associated phenotype.Molecular cytogenetics · 2014Article
- SUMOylation in neuroplasticity and neurological disorders.Neuromolecular medicine · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Small ubiquitin-like modifiers (SUMOs) are polypeptides resembling ubiquitin that are covalently attached to specific lysine residue of target proteins through a specific enzymatic pathway. Sumoylation is now seen as a key posttranslational modification involved in many biological processes, but little is known about how this highly dynamic protein modification is regulated in the brain. Disruption of the sumoylation enzymatic pathway during the embryonic development leads to lethality revealing a pivotal role for this protein modification during development. The main aim of this review is to briefly describe the SUMO pathway and give an overview of the sumoylation regulations occurring in brain development, neuronal morphology and synapse formation.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.