ArticlePituitary2014
Endoscopic endonasal approach for pituitary adenomas: a series of 555 patients.
Article in Pituitary, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 86 papers, 8 of them syntheses that pooled it.
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Who cites it
86 citing papers in PubMed, 8 syntheses or guidelines pooled it, 253 citations in OpenAlex.
- Recurrent acromegaly: a systematic review on therapeutic approaches.BMC endocrine disorders · 2024Pooled it
- The incidence of postoperative cerebrospinal fluid leakage after elective cranial surgery: a systematic review.Neurosurgical review · 2022Pooled it
- Pooled it
- Guidelines in the management of CNS tumors.Journal of neuro-oncology · 2021Guideline
- Endoscopic vs. microscopic transsphenoidal surgery for Cushing's disease: a systematic review and meta-analysis.Pituitary · 2018Pooled it
- Microsurgical versus endoscopic transsphenoidal resection for acromegaly: a systematic review of outcomes and complications.Acta neurochirurgica · 2017Pooled it
- Visual outcomes after endoscopic endonasal pituitary adenoma resection: a systematic review and meta-analysis.Pituitary · 2017Pooled it
- Endoscopic Endonasal Versus Microscopic Transsphenoidal Surgery for Recurrent and/or Residual Pituitary Adenomas.World neurosurgery · 2017Pooled it
- Free middle turbinate mucosal graft reconstruction after primary endoscopic endonasal pituitary surgery.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2017Trial
- Pedicled Nasoseptal Flap After Endoscopic Endonasal Resection of Skull Base Tumors: A Comparative Meta-Analysis with Other Modalities of Reconstruction.Journal of neurological surgery. Part B, Skull base · 2026Article
- Postoperative CSF Characteristics After Extended Endoscopic Skull Base Surgery: Case Series and Review of the Literature.Journal of neurological surgery. Part B, Skull base · 2026Article
- Olfactory-Related Quality of Life After Endoscopic Transsphenoidal Surgery.Laryngoscope investigative otolaryngology · 2026Article
- Very Long-Term Follow-Up of Multidimensional Health-Related Quality of Life After Endoscopic Endonasal Surgery for Pituitary Adenomas: A Prospective Cohort Study.Head & neck · 2026Article
- Clinical predictors of postoperative cerebrospinal fluid leakage following endoscopic endonasal surgery for pituitary neuroendocrine tumors: a retrospective cohort study.BMC neurology · 2026Article
- Article
- Pneumocephalus and delayed hydrocephalus following endoscopic endonasal biopsy of skull base lesion: diagnostic pitfalls and the role of immunohistochemistry.Archive of clinical cases · 2026Article
- Machine Learning Prediction of Pituitary Macroadenoma Consistency: Utilizing Demographic Data and Brain MRI Parameters.Journal of imaging informatics in medicine · 2025Article
- Endoscopic Transsphenoidal Sellar Surgery via One Nostril: Own Experience and Systematic Review of the Literature.Life (Basel, Switzerland) · 2025Review
- Endoscopic endonasal transcavernous surgery for a contemporary series of 59 prolactinomas.Pituitary · 2025Article
- A Narrative Review of Surgery for Prolactinomas: Considerations and Controversies.Journal of clinical medicine · 2025Review
26 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo report the results of a consecutive series of patients who underwent an endoscopic endonasal approach (EEA) for resection of a pituitary adenoma and compare them to previous series of microscopic and endoscopic approaches.
methodsA retrospective review of clinical and radiographic outcomes of a consecutive series of patients operated at our center between 2002 and 2011 was performed.
results555 patients underwent an EEA for removal of a pituitary adenoma. The mean follow up was 3.1 years (range 3 months to 9.5 years); 36 were lost to follow up. Ninety-one (17.5%) harbored recurrent adenomas. An expanded approach to reach the supra-, para- and infra-sellar spaces was employed in 290 patients (55.9%). Reconstruction with a nasal septal flap was used in 238 cases (65.6%). The rate of gross total resection was 65.3% in the 359 patients with non-functioning adenomas. The remission rates with EEA alone were 82.5% in the 57 ACTH-secreting adenomas, 65.3% in the 49 GH-secreting adenomas and 54.7% in the 53 prolactinomas. Of the 237 patients presenting with visual loss, 190 (80.2%) improved or normalized, 41 (17.3%) remained unchanged and 4 (1.7%) experienced transient visual deterioration due to postoperative apoplexy. In addition, no patient without preexisting visual loss suffered new visual decline. The overall post-operative CSF leak rate was 5% and this decreased to 2.9% after the introduction of reconstruction with the naso-septal flap. Two patients (0.3%) had an ICA injury.
conclusionsThe EEA is a safe and effective way to surgically approach pituitary adenomas, particularly in recurrent tumors, those with supra-sellar extension or cavernous sinus invasion. The remission and complication rates are comparable or favorable compared with those reported in previous series of microscopic and endoscopic approaches.
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