Evidence map›Paper›PMID 23905162›Full record

ArticleThe Analyst2013

Detection of IP-10 protein marker in undiluted blood serum via an electrochemical E-DNA scaffold sensor.

Andrew J Bonham, Nicole G Paden, Francesco Ricci, Kevin W Plaxco

Abstract read
In one paragraph

Article in The Analyst, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Rationally Designed DNA-Based Scaffolds and Switching Probes for Protein Sensing.Advances in biochemical engineering/biotechnology · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Andrew J BonhamDepartment of Chemistry, Metropolitan State University of Denver, Denver, CO 80217, USA. abonham@msudenver.edu.
Nicole G Paden
Francesco Ricci
Kevin W Plaxco

Funding

Rapid detection of diagnostic chemokinesR01AI076899 · NIAID · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI PLAXCO, KEVIN W · 2010 to 2014
$1.7M
Electrochemical arrays for the detection of small molecule drugsR01EB007689 · NIBIB · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI PLAXCO, KEVIN W · 2008 to 2011
$1.3M
NIAID NIH HHS R01 AI076899NIBIB NIH HHS R01 EB007689NIBIB NIH HHS R01EB007689
6 · The paper itself

Abstract

We describe an electrochemical analog of fluorescence polarization that supports the quantitative measurement of a specific protein, the chemokine IP-10, directly in undiluted blood serum. The sensor is label-free, wash-free, and electronic, suggesting it could support point-of-care detection of diagnostic proteins in largely unprocessed clinical samples.

Indexed as

BiomarkersChemokine CXCL10DNAElectrochemical TechniquesHumansProtein Structure, SecondarySerumBiomarkersChemokine CXCL10CXCL10 protein, humanDNA

Identifiers

PMID23905162
PMCPMC3956051

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.