Evidence map›Paper›PMID 23904886›Full record

ArticleJournal of medicine and life2013

Analysis of the visual evoked potential in anesthesia with sevoflurane and chloral hydrate : (Variability of amplitudes, latencies and morphology of VEP with the depth of anesthesia).

A M Ghita, D Parvu, R Sava, L Georgescu, L Zagrean

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Article in Journal of medicine and life, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact, top 98% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

A M GhitaUniversity Emergency Hospital Bucharest, Romania. ghita.mihai@univermed-cdgm.ro
D Parvu
R Sava
L Georgescu
L Zagrean
Clinical Emergency Hospital Bucharest · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

unlabelledThe visually evoked potential (VEP) is an electrical signal generated by the occipital cortex in response to light stimulation of the retina. The clinical importance of the VEP consists in the diagnosis of optic nerve diseases and others ocular diseases. For experimental studies of VEP in experimental animals anesthesia is frequently required. Our study sought VEP changes depending on the type and depth of anesthesia.

methodsthis study evaluated VEPs in 20 Wistar rats under two anesthetics. Ten rats were anesthetized with sevoflurane and ten rats with chloral hydrate.

resultsThe amplitudes, latencies and morphology of the VEP varied with the depth of anesthesia. The latency of VEP increases with the depth of anesthesia and the amplitude of the waves becomes more positive once the anesthesia decreases under sevoflurane and more negative under chloral hydrate. The variability of VEP was different under the two anesthetics with greater peak latencies under sevoflurane than under chloral hydrate at the same depth of anesthesia. IN

conclusionit is important to know the influence of the anesthetic and the depth of anesthesia over VEPS, because they may constitute a confounding factor in studying VEP in different diseases of optic nerve or eyeball.

Indexed as

AnesthesiaAnimalsChloral HydrateEvoked Potentials, VisualMaleMethyl EthersRatsRats, WistarSevofluraneChloral HydrateMethyl EthersSevofluranechloral hydratesevofluranevisual evoked potentials

Identifiers

PMID23904886
PMCPMC3725452
OpenAlexW297206961

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.