ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2013
Orientation-selective responses in the mouse lateral geniculate nucleus.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 90 papers.
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90 citing papers in PubMed.
- Rapid robust high-fidelity 3D neuronal extraction from multiview calcium imaging datasets.Nature methods · 2026Article
- Spatial biases in visual feature representation of mouse dorsal lateral geniculate nucleus boutons.iScience · 2026Article
- Laminar-specific control of response gain and orientation-tuning by parvalbumin-expressing inhibitory interneurons in primate visual cortex.Research square · 2026Article
- Orientation Maps in Mouse Superior Colliculus Explained by Population Model of Non-Orientation Selective Neurons.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Optogenetic stimulation of pyramidal neurons in the rat primary visual cortex modulates ON- and OFF- receptive field areas independently.Scientific reports · 2025Article
- A Neural Model for V1 That Incorporates Dendritic Nonlinearities and Backpropagating Action Potentials.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Differential topographic organization and retinal inheritance of direction and orientation selectivity in the visual thalamus.Nature communications · 2025Article
- Coordination of distinct sources of excitatory inputs enhances motion selectivity in the mouse visual thalamus.Neuron · 2025Article
- Limited transmission of mixed convergent signals at the mouse retinogeniculate synapse.Neuron · 2025Article
- Experience influences the refinement of feature selectivity in the mouse primary visual thalamus.Neuron · 2025Article
- Long-term intravital subcellular imaging with confocal scanning light-field microscopy.Nature biotechnology · 2025Article
- Cross-Frequency Couplings Reveal Mice Visual Cortex Selectivity to Grating Orientations.Brain and behavior · 2025Article
- Compartmentalized pooling generates orientation selectivity in wide-field amacrine cells.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Population coding of auditory space in the dorsal inferior colliculus persists with altered binaural cues.bioRxiv : the preprint server for biology · 2024Article
- Decoding dynamic visual scenes across the brain hierarchy.PLoS computational biology · 2024Article
- Stimulus edges induce orientation tuning in superior colliculus.Nature communications · 2023Article
- Retinal waves align the concentric orientation map in mouse superior colliculus to the center of vision.Science advances · 2023Article
- Impact of Acute Visual Experience on Development of LGN Receptive Fields in the Ferret.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Sound Improves Neuronal Encoding of Visual Stimuli in Mouse Primary Visual Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Haploinsufficiency of Shank3 increases the orientation selectivity of V1 neurons.Scientific reports · 2022Article
30 more citing papers are in PubMed but not listed here.
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4 authors.
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Abstract
The dorsal lateral geniculate nucleus (dLGN) receives visual information from the retina and transmits it to the cortex. In this study, we made extracellular recordings in the dLGN of both anesthetized and awake mice, and found that a surprisingly high proportion of cells were selective for stimulus orientation. The orientation selectivity of dLGN cells was unchanged after silencing the visual cortex pharmacologically, indicating that it is not due to cortical feedback. The orientation tuning of some dLGN cells correlated with their elongated receptive fields, while in others orientation selectivity was observed despite the fact that their receptive fields were circular, suggesting that their retinal input might already be orientation selective. Consistently, we revealed orientation/axis-selective ganglion cells in the mouse retina using multielectrode arrays in an in vitro preparation. Furthermore, the orientation tuning of dLGN cells was largely maintained at different stimulus contrasts, which could be sufficiently explained by a simple linear feedforward model. We also compared the degree of orientation selectivity in different visual structures under the same recording condition. Compared with the dLGN, orientation selectivity is greatly improved in the visual cortex, but is similar in the superior colliculus, another major retinal target. Together, our results demonstrate prominent orientation selectivity in the mouse dLGN, which may potentially contribute to visual processing in the cortex.
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