ReviewAnnals of botany2013
A tale of two toxicities: malformed selenoproteins and oxidative stress both contribute to selenium stress in plants.
Review in Annals of botany, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers.
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Who cites it
73 citing papers in PubMed.
- Effect of selenium hyperaccumulation on the root endophytic and rhizosphere microbiome of two Astragalus species.Plant biology (Stuttgart, Germany) · 2026Article
- Effects of Partial Replacing Fish Meal with Dietary Degossypolled Cottonseed Protein on Growth Performance, Intestinal Barrier, Immune Function and Antioxidant Response in Largemouth Bass (Animals : an open access journal from MDPI · 2026Article
- Sodium selenate stimulates growth and photosynthetic pigments in sweet potato plantlets in vitro.BMC research notes · 2026Article
- Development and Optimisation of an HPLC-MS/MS Workflow for Profiling Selenium and Sulphur Amino Acids in Soybean Leaves and Investigation of Se-S Metabolic Interactions.Molecules (Basel, Switzerland) · 2026Article
- An atlas of plant selenium metabolism.The New phytologist · 2026Review
- Foliar Application of Selenium in Mitigating Salinity Stress on the Physiology, Growth, and Yield of Okra.Plants (Basel, Switzerland) · 2025Article
- Selenium and Sulphur as Elements Modifying Plant Quality: Assessment of the Content of Organic and Mineral Nitrogen Forms in Wheat.Molecules (Basel, Switzerland) · 2025Article
- Integrated transcriptomics and metabolomics reveal key metabolic pathway responses in Mentha Piperita L. under selenite stress.BMC plant biology · 2025Article
- Enhancing Nutritional and Functional Properties of Hydroponically Grown Underutilised Leafy Greens Through Selenium Biofortification.Plants (Basel, Switzerland) · 2025Article
- Improvement of cereal- and legume-derived protein quality with selenium and sulfur for plant food production.Journal of the science of food and agriculture · 2025Review
- Selenium Biotransformation and Fractionation of Selenopeptide from Germinated Perilla (Foods (Basel, Switzerland) · 2025Article
- Astral-based DIA proteomics analysis reveals the effects of selenium on Pleurotus pulmonarius.Scientific reports · 2025Article
- Integrating molecular mechanisms and agronomic strategies for selenium biofortification in horticultural crops.Frontiers in plant science · 2025Review
- Plant hyperaccumulators: a state-of-the-art review on mechanism of heavy metal transport and sequestration.Frontiers in plant science · 2025Review
- The curious case of selenium hyperaccumulation in Coelospermum decipiens from the Cape York Peninsula (Queensland, Australia).Annals of botany · 2024Article
- Allelic variation of TaABI5-A4 significantly affects seed dormancy in bread wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Article
- Genetic Biofortification of Winter Wheat with Selenium (Se).Plants (Basel, Switzerland) · 2024Review
- Screening and Identification of Soil Selenium-Enriched Strains and Application inMicroorganisms · 2024Article
- Selenium-Induced Enhancement in Growth and Rhizosphere Soil Methane Oxidation of Prickly Pear.Plants (Basel, Switzerland) · 2024Article
- Transcriptome analysis reveals the promoting effects of exogenous melatonin on the selenium uptake in grape under selenium stress.Frontiers in plant science · 2024Article
13 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDespite selenium's toxicity in plants at higher levels, crops supply most of the essential dietary selenium in humans. In plants, inorganic selenium can be assimilated into selenocysteine, which can replace cysteine in proteins. Selenium toxicity in plants has been attributed to the formation of non-specific selenoproteins. However, this paradigm can be challenged now that there is increasingly abundant evidence suggesting that selenium-induced oxidative stress also contributes to toxicity in plants. SCOPE: This Botanical Briefing summarizes the evidence indicating that selenium toxicity in plants is attributable to both the accumulation of non-specific selenoproteins and selenium-induced oxidative stress. Evidence is also presented to substantiate the claim that inadvertent selenocysteine replacement probably impairs or misfolds proteins, which supports the malformed selenoprotein hypothesis. The possible physiological ramifications of selenoproteins and selenium-induced oxidative stress are discussed.
conclusionsMalformed selenoproteins and oxidative stress are two distinct types of stress that drive selenium toxicity in plants and could impact cellular processes in plants that have yet to be thoroughly explored. Although challenging, deciphering whether the extent of selenium toxicity in plants is imparted by selenoproteins or oxidative stress could be helpful in the development of crops with fortified levels of selenium.
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