ArticleEuropean radiology2013
Benefits of contrast-enhanced SWI in patients with glioblastoma multiforme.
Article in European radiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 32 citations in OpenAlex.
- Post-contrast Susceptibility Weighted Imaging in Multiple Sclerosis MRI Improves the Detection of Enhancing Lesions.Clinical neuroradiology · 2025Article
- Diagnostic Utility of Intratumoral Susceptibility Signals in Adult Diffuse Gliomas: Tumor Grade Prediction and Correlation with Molecular Markers Within the WHO CNS5 (2021) Classification.Journal of clinical medicine · 2025Article
- An update on susceptibility-weighted imaging in brain gliomas.European radiology · 2024Review
- Advanced MR Techniques for Preoperative Glioma Characterization: Part 2.Journal of magnetic resonance imaging : JMRI · 2023Review
- Peliminary exploration on the differential diagnosis between meningioma and schwannoma using contrast-enhanced TFrontiers in oncology · 2022Article
- Clinical Value of Susceptibility Weighted Imaging of Brain Metastases.Frontiers in neurology · 2020Review
- Impact on survival of early tumor growth between surgery and radiotherapy in patients with de novo glioblastoma.Journal of neuro-oncology · 2019Article
- Gadolinium-Enhanced Susceptibility-Weighted Imaging in Multiple Sclerosis: Optimizing the Recognition of Active Plaques for Different MR Imaging Sequences.AJNR. American journal of neuroradiology · 2019Observational
- Multi-parametric effect in predicting tumor histological grade by using susceptibility weighted magnetic resonance imaging in tongue squamous cell carcinoma.BMC medical imaging · 2019Article
- Glioma imaging in Europe: A survey of 220 centres and recommendations for best clinical practice.European radiology · 2018Article
- The T1 shine through effect on susceptibility weighted imaging: an under recognized phenomenon.Neuroradiology · 2018Article
- Multimodal Imaging of Patients With Gliomas ConfirmsMolecular imaging · 2017Article
- Discriminating pyogenic brain abscesses, necrotic glioblastomas, and necrotic metastatic brain tumors by means of susceptibility-weighted imaging.European radiology · 2015Article
- Susceptibility-weighted imaging of the venous networks around the brain stem.Neuroradiology · 2015Article
- Focal hemodynamic patterns of status epilepticus detected by susceptibility weighted imaging (SWI).European radiology · 2014Article
- Emerging Techniques in Brain Tumor Imaging: What Radiologists Need to Know.Korean journal of radiologyReview
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionSWI can help to identify high-grade gliomas (HGG). The objective of this study was to analyse SWI and CE-SWI characteristics, i.e. the relationship between contrast-induced phase shifts (CIPS) and intratumoral susceptibility signals (ITSS) and their association with tumour volume in patients with glioblastoma multiforme (GBM). MATERIALS AND
methodsMRI studies of 29 patients were performed to evaluate distinct susceptibility signals comparing SWI and CE-SWI characteristics. The relationship between these susceptibility signals and CE-T1w tumour volume was analysed by using Spearman's rank correlation coefficient and Kruskal-Wallis-test. Tumour biopsies of different susceptibility signals were performed in one patient.
resultsComparison of SWI and CE-SWI demonstrated different susceptibility signals. Susceptibility signals visible on SWI images are consistent with ITSS; those only seen on CE-SWI were identified as CIPS. Correlation with CE-T1w tumour volume revealed that CIPS were especially present in small or medium-sized GBM (Spearman's rho r = 0.843, P < 0.001). Histology identified the area with CIPS as the tumour invasion zone, while the area with ITSS represented micro-haemorrhage, highly pathological vessels and necrosis.
conclusionCE-SWI adds information to the evaluation of GBM before therapy. It might have the potential to non-invasively identify the tumour invasion zone as demonstrated by biopsies in one case. KEY POINTS: • MRI is used to help differentiate between low- and high-grade gliomas. • Contrast-enhanced susceptibility-weighted MRI (CE-SWI) helps to identify patients with glioblastoma multiforme. • CE-SWI delineates the susceptibility signal (CIPS and ITSS) more than the native SWI. • CE-SWI might have the potential to non-invasively identify the tumour invasion zone.
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