ArticleJournal of clinical microbiology2013
Clinical significance and molecular characterization of nonsporulating molds isolated from the respiratory tracts of bronchopulmonary mycosis patients with special reference to basidiomycetes.
Article in Journal of clinical microbiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed, 63 citations in OpenAlex.
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- Subcutaneous abscess caused byMedical mycology case reports · 2026Article
- Chronic Pulmonary Aspergillosis Caused by Aspergillus tubingensis Diagnosed by a Bronchoscopic Biopsy.Internal medicine (Tokyo, Japan) · 2024Article
- Allergic bronchopulmonary mycosis caused byRespiratory medicine case reports · 2024Article
- Subcutaneous mycosis caused by filamentous basidiomyceteMedical mycology case reports · 2023Article
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- Diversity and Metabolic Activity of Fungi Causing Biodeterioration of Canvas Paintings.Journal of fungi (Basel, Switzerland) · 2022Article
- Production of Volatile Compounds by a Variety of Fungi in Artificially Inoculated and Naturally Infected Aquilaria malaccensis.Current microbiology · 2022Article
- Rigidoporus corticola Colonization and Invasive Fungal Disease in Immunocompromised Patients, United States.Emerging infectious diseases · 2022Article
- Diversity and Drug Resistance of Filamentous Fungi Isolated from the Fresh Raspberries.Indian journal of microbiology · 2022Article
- Fungal populations in the bedroom dust of children in Havana, Cuba, and its relationship with environmental conditions.Environmental science and pollution research international · 2021Article
- Dietary supplementation withFood science and biotechnology · 2021Article
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- The Unrelenting Non-sporulating Hyphae.Cureus · 2021Article
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- Five Korean Cases of Respiratory Tract Infection by Filamentous Basidiomycetes.Annals of laboratory medicine · 2020Article
- A Case of Fungus Ball-Type Maxillary Sinusitis Due to Penicillium Roqueforti.Mycopathologia · 2018Article
- Eosinophilic plasmacytic conjunctivitis concurrent with gingival fistula caused byMedical mycology case reports · 2017Article
- Schizophyllum radiatum, an Emerging Fungus from Human Respiratory Tract.Journal of clinical microbiology · 2016Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nonsporulating molds (NSMs), especially basidiomycetes, have predominantly been reported as human pathogens responsible for allergic and invasive disease. Their conventional identification is problematic, as many isolates remain sterile in culture. Thus, inconclusive culture reports might adversely affect treatment decisions. The clinical significance of NSMs in pulmonary mycoses is poorly understood. We sequenced the internal transcribed spacer (ITS) region and D1/D2 domain of the larger subunit (LSU) of 52 NSMs isolated from respiratory specimens. The basidiomycetes were the predominant NSMs, of which Schizophyllum commune was the most common agent in allergic bronchopulmonary mycosis (ABPM), followed by Ceriporia lacerata in invasive fungal disease. Porostereum spadiceum, Phanaerochaete stereoides, Neosartorya fischeri, and Marasmiellus palmivorus were the other molds observed. Application of ITS and LSU region sequencing identified 92% of the isolates. The antifungal susceptibility data revealed that all basidiomycetes tested were susceptible to amphotericin B and resistant to caspofungin, fluconazole, and flucytosine. Except for 3 isolates of S. commune and a solitary isolate of M. palmivorus, all basidiomycetes had low MICs for itraconazole, posaconazole, and voriconazole. Basidiomycetes were isolated from patients with ABPM, invasive pulmonary mycosis/pneumonia, or fungal balls. In addition, the majority of the basidiomycetes were isolated from patients with chronic respiratory disorders who were sensitized to one of the basidiomycetous fungi and demonstrated precipitating antibodies against the incriminating fungi, indicating an indolent tissue reaction. Thus, isolation of basidiomycetes from the lower respiratory tract could be significant, and it is important to monitor these patients in order to prevent subsequent lung damage.
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