ArticleChemical communications (Cambridge, England)2013
[Gd(CyPic3A)(H2O)2]-: a stable, bis(aquated) and high-relaxivity Gd(III) complex.
Article in Chemical communications (Cambridge, England), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Computational insight into a mechanistic overview of water exchange kinetics and thermodynamic stabilities of bis and tris-aquated complexes of lanthanides.RSC advances · 2023Article
- Surprising Complexity of the [Gd(AAZTA)(HInorganic chemistry · 2022Article
- Molecular Magnetic Resonance Imaging with Gd(III)-Based Contrast Agents: Challenges and Key Advances.Journal of the American Chemical Society · 2019Review
- Cyclobutane-Containing Scaffolds as Useful Intermediates in the Stereoselective Synthesis of Suitable Candidates for Biomedical Purposes: Surfactants, Gelators and Metal Cation Ligands.International journal of molecular sciences · 2019Article
- Ligand design strategies to increase stability of gadolinium-based magnetic resonance imaging contrast agents.Nature communications · 2019Review
- Chemistry of MRI Contrast Agents: Current Challenges and New Frontiers.Chemical reviews · 2019Review
- MR imaging probes: design and applications.Dalton transactions (Cambridge, England : 2003) · 2015Review
- Probing the structure-relaxivity relationship of bis-hydrated Gd(DOTAla) derivatives.Inorganic chemistry · 2015Article
- Overcoming the concentration-dependence of responsive probes for magnetic resonance imaging.Metallomics : integrated biometal science · 2015Review
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
We report the synthesis and MR relevant properties of CyPic3A, a heptadentate chelator that forms ternary Gd(III) complexes of hydration state q = 2. [Gd(CyPic3A)(H2O)2](-) affords an r1 value of 5.70 mM(-1) s(-1) at 1.41 T and 310 K and displays thermodynamic stability and kinetic inertness comparable to FDA approved MR imaging probes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.