Trial reportBMJ (Clinical research ed.)2013
Impact of wound edge protection devices on surgical site infection after laparotomy: multicentre randomised controlled trial (ROSSINI Trial).
Trial report in BMJ (Clinical research ed.), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 119 papers, 18 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Determining the Worldwide Epidemiology of Surgical Site Infections After Gastrointestinal Surgery
Randomized Controlled Trial to Evaluate the Effectiveness and Efficacy of a Sterile Circular Polyethylene Drape Compared to Conventional Surgical Dressing in Prevention of Surgical Site Infection
Who cites it
119 citing papers in PubMed, 18 syntheses or guidelines pooled it, 270 citations in OpenAlex.
- European Guideline on Pre-Operative Prevention of Surgical Site Infections Following Digestive Surgery: A Joint Update of the WHO SSI Guideline for Gastrointestinal Surgery by UEG, ESCP, EAES, and SIS-E.United European gastroenterology journal · 2025Guideline
- Systematic review and meta-analysis of outcomes associated with incisional and organ/space surgical site infections in abdominal surgery patients.Antimicrobial resistance and infection control · 2025Pooled it
- A Systematic Review of Health-Related Quality-of-Life Measurement in Patients With Acute Bacterial Skin and Skin Structure Infections.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2025Pooled it
- Role of wound protectors in preventing surgical site infection in patients undergoing abdominal surgery: a meta-analysis of randomized controlled trials.BMC surgery · 2025Pooled it
- Prognostic models for surgical-site infection in gastrointestinal surgery: systematic review.The British journal of surgery · 2023Pooled it
- Association Between Antibiotic Prophylaxis Before Cystectomy or Stent Removal and Infection Complications: A Systematic Review.European urology focus · 2023Pooled it
- Use of Telemedicine for Postdischarge Assessment of the Surgical Wound: International Cohort Study, and Systematic Review With Meta-analysis.Annals of surgery · 2023Pooled it
- The clinical effectiveness of wound edge protectors in reducing surgical site infection after abdominal surgery: meta-analysis.BJS open · 2022Pooled it
- Prophylactic negative pressure wound therapy for closed laparotomy wounds: a systematic review and meta-analysis of randomised controlled trials.Irish journal of medical science · 2021Pooled it
- The Japan Society for Surgical Infection: guidelines for the prevention, detection, and management of gastroenterological surgical site infection, 2018.Surgery today · 2021Pooled it
- Global incidence of surgical site infection after appendectomy: a systematic review and meta-analysis.BMJ open · 2020Pooled it
- Surgical site infection and costs in low- and middle-income countries: A systematic review of the economic burden.PloS one · 2020Pooled it
- APSIC guidelines for the prevention of surgical site infections.Antimicrobial resistance and infection control · 2019Guideline
- Wound protectors in reducing surgical site infections in lower gastrointestinal surgery: an updated meta-analysis.Surgical endoscopy · 2018Pooled it
- Methodological overview of systematic reviews to establish the evidence base for emergency general surgery.The British journal of surgery · 2017Pooled it
- A systematic review of clinical effectiveness of wound edge protector devices in reducing surgical site infections in patients undergoing abdominal surgery.Updates in surgery · 2017Pooled it
- Intra-operative wound irrigation to reduce surgical site infections after abdominal surgery: a systematic review and meta-analysis.Langenbeck's archives of surgery · 2015Pooled it
- Wound edge protectors in open abdominal surgery to reduce surgical site infections: a systematic review and meta-analysis.PloS one · 2015Pooled it
- Alexis O-ring wound retractor versus traditional metal retractors for the prevention of postcaesarean surgical site infections.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2023Trial
- Prophylactic biological mesh reinforcement versus standard closure of stoma site (ROCSS): a multicentre, randomised controlled trial.Lancet (London, England) · 2020Trial
59 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors at 3 institutions in 1 country.
Funding
Abstract
objectiveTo determine the clinical effectiveness of wound edge protection devices in reducing surgical site infection after abdominal surgery.
designMulticentre observer blinded randomised controlled trial.
participantsPatients undergoing laparotomy at 21 UK hospitals.
interventionsStandard care or the use of a wound edge protection device during surgery.
main outcome measuresSurgical site infection within 30 days of surgery, assessed by blinded clinicians at seven and 30 days and by patient's self report for the intervening period. Secondary outcomes included quality of life, duration of stay in hospital, and the effect of characteristics of the patient and operation on the efficacy of the device.
results760 patients were enrolled with 382 patients assigned to the device group and 378 to the control group. Six patients in the device group and five in the control group did not undergo laparotomy. Fourteen patients, seven in each group, were lost to follow-up. A total of 184 patients experienced surgical site infection within 30 days of surgery, 91/369 (24.7%) in the device group and 93/366 (25.4%) in the control group (odds ratio 0.97, 95% confidence interval 0.69 to 1.36; P=0.85). This lack of benefit was consistent across wound assessments performed by clinicians and those reported by patients and across all secondary outcomes. In the secondary analyses no subgroup could be identified in which there was evidence of clinical benefit associated with use of the device.
conclusionsWound edge protection devices do not reduce the rate of surgical site infection in patients undergoing laparotomy, and therefore their routine use for this role cannot be recommended.
trial registrationCurrent Controlled Trials ISRCTN 40402832.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.