ArticleBMC cancer2013
First description of seasonality of birth and diagnosis amongst teenagers and young adults with cancer aged 15-24 years in England, 1996-2005.
Article in BMC cancer, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Observations on seasonal occurrence in lymphomas with proven or presumed infectious etiology.Frontiers in oncology · 2025Article
- Does month of birth influence colorectal cancer prognosis?Langenbeck's archives of surgery · 2023Observational
- Seasonal variation in the incidence of primary CNS lymphoma.Neuro-oncology practice · 2020Article
- Article
- Perinatal Light Imprinting of Circadian Clocks and Systems (PLICCS): The PLICCS and Cancer Hypothesis.Frontiers in oncology · 2017Article
- Population mixing and incidence of cancers in adolescents and young adults between 1990 and 2013 in Yorkshire, UK.Cancer causes & control : CCC · 2016Article
- Perinatal risk factors for acute myeloid leukemia.European journal of epidemiology · 2015Article
- Do human tumor-associated viruses play a role in the development of synovial sarcoma?Clinical sarcoma research · 2015Article
- Season of birth and risk of Hodgkin and non-Hodgkin lymphoma.International journal of cancer · 2014Article
- Seasonal variation in the month of birth in patients with skin cancer.British journal of cancer · 2014Article
- Population mixing for leukaemia, lymphoma and CNS tumours in teenagers and young adults in England, 1996-2005.BMC cancer · 2014Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWe aimed to examine evidence for an infectious aetiology among teenagers and young adults (TYA) by analysing monthly seasonality of diagnosis and birth amongst 15-24 year olds diagnosed with cancer in England.
methodsCases of leukaemia, lymphoma and central nervous system (CNS) tumours were derived from the national TYA cancer register (1996-2005). Incidence rates (IR) and trends were assessed using Poisson regression. Seasonality of diagnosis and birth was assessed using Poisson and logistic regression respectively with cosine functions of varying periods.
resultsThere were 6251 cases diagnosed with leukaemia (n = 1299), lymphoma (n = 3070) and CNS tumours (n = 1882), the overall IR was 92 (95% CI 89-96) per 1,000,000 15-24 year olds per year.There was significant evidence of seasonality around the time of diagnosis for Hodgkin's lymphoma (P < 0.001) with a peak in February, and for 'other CNS tumours' (P = 0.010) with peaks in December and June. Birth peaks for those with 'other Gliomas' (Gliomas other than Astrocytoma and Ependymoma) were observed in May and November (P = 0.015).
conclusionOur novel findings support an infectious aetiological hypothesis for certain subgroups of TYA cancer in England. Further work will examine correlation with specific infections occurring around the time of birth and diagnosis within certain diagnostic groups.
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