Evidence map›Paper›PMID 23902649›Full record

ReviewJournal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance2013

Understanding cardiovascular injury after treatment for cancer: an overview of current uses and future directions of cardiovascular magnetic resonance.

Sujethra Vasu, W Gregory Hundley

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03935282 (Assessing Effectiveness and Implementation of an EHR Tool to Assess Heart Health Among Survivors), which is not on this map. Cited by 30 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 2 pooled it
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03935282 nacompletednot on this mapstarted 2020, after this paper: background citation

Assessing Effectiveness and Implementation of an EHR Tool to Assess Heart Health Among Survivors (AH-HA)

TypeinterventionalSponsorWake Forest University Health SciencesRan2020 to 2025Enrolled645ConditionsBreast Neoplasm, Prostatic Neoplasm, Colorectal Neoplasms, Endometrial NeoplasmsArmsAH-HA Tool in the EPIC EHR
3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 2 syntheses or guidelines pooled it, 51 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Toward a Better Understanding of the Differential Impact of Heart Failure Phenotypes After Breast Cancer.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2022
    Article
  6. Article
  7. Observational
  8. The Role of Cardiac MRI in Animal Models of Cardiotoxicity: Hopes and Challenges.Journal of cardiovascular translational research · 2020
    Review
  9. Management of cardiac disease in cancer patients throughout oncological treatment: ESMO consensus recommendations.Annals of oncology : official journal of the European Society for Medical Oncology · 2020
    Article
  10. Multimodality Cardiac Imaging in the Era of Emerging Cancer Therapies.Journal of the American Heart Association · 2020
    Review
  11. Article
  12. Review
  13. Observational
  14. Article
  15. Cardiovascular imaging in cardio-oncology.Journal of thoracic disease · 2018
    Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. The Role of Cardiovascular Magnetic Resonance in the Management of Patients with Cancer.Current treatment options in cardiovascular medicine · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Sujethra Vasu
W Gregory Hundley
Wake Forest University · US

Funding

Wake Forest Claude D. Pepper OAIC - RenewalP30AG021332 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Jamie Nicole Justice · 2002 to 2026
$36.4M
Vascular Stiffness and Pulmonary CongestionR01HL076438 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI HUNDLEY, WILLIAM GREGORY · 2007 to 2011
$3.2M
Early Imaging Detection of CV Injury after CancerR01CA167821 · NCI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI HUNDLEY, WILLIAM GREGORY, JOLLY, MARIE-PIERRE · 2012 to 2016
$2.5M
Optimized CMR imaging of chemotherapy cardiotoxicityR33CA121296 · NCI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI HUNDLEY, WILLIAM GREGORY · 2007 to 2009
$716k
Multidisciplinary Training in Cardiovascular ImagingT32HL091824 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI HUNDLEY, WILLIAM GREGORY · 2009 to 2013
$707k
NCI NIH HHS R01 CA167821NCI NIH HHS R33 CA121296NHLBI NIH HHS R01 HL076438NHLBI NIH HHS T32 HL091824NIA NIH HHS P30 AG21332
6 · The paper itself

Abstract

While cancer-free survival has improved over the past 20 years for many individuals with prostate, renal, breast, and hematologic malignancies, the increasingly recognized prevalence of cardiovascular (CV) events in cancer survivors has been an unintended consequence of many of the therapies that have improved these survival rates. The increase in CV events threatens to offset the improvement in cancer related survival. As a result, there is an emerging need to develop methods to identify those individuals treated for cancer at increased risk of cardiovascular events. With its inherent ability to characterize myocardial tissue and identify both cardiac and vascular dysfunction, cardiovascular magnetic resonance (CMR) has the potential to identify both subclinical and early clinical CV injury before the development of an overt catastrophic event such as a myocardial infarction, stroke, or premature cardiac death. Early identification provides an opportunity for the implementation of primary prevention strategies to prevent such events, thereby improving overall cancer survivorship and quality of life. This article reviews the etiology of CV events associated with cancer therapy and the unique potential of CMR to provide early diagnosis of subclinical CV injury related to the administration of these therapies.

Indexed as

Magnetic Resonance ImagingAnimalsAntineoplastic AgentsCardiovascular DiseasesCardiovascular SystemEarly DiagnosisHumansPredictive Value of TestsPrognosisRisk AssessmentRisk FactorsSurvivorsAntineoplastic Agents

Identifiers

PMID23902649
PMCPMC3765662
OpenAlexW2017626575

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.