Evidence map›Paper›PMID 23902226›Full record

ArticleClinical transplantation

Measuring and explaining racial and ethnic differences in willingness to donate live kidneys in the United States.

Tanjala S Purnell, Neil R Powe, Misty U Troll, Nae-Yuh Wang, Carlton Haywood, Thomas A LaVeist, L Ebony Boulware

Abstract readComparative Study
In one paragraph

Article in Clinical transplantation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Acceptability of a Mobile-Health Living Kidney Donor Advocacy Program for Black Wait-Listed Patients.International journal of environmental research and public health · 2021
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  16. Race and Mortality in CKD and Dialysis: Findings From the Chronic Renal Insufficiency Cohort (CRIC) Study.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tanjala S PurnellDivision of General Internal Medicine, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA; Department of Health Policy and Management, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA; Welch Center for Prevention, Epidemiology and Clinical Research, Johns Hopkins Medical Institutions, Baltimore, MD, USA.
Neil R Powe
Misty U Troll
Nae-Yuh Wang
Carlton Haywood
Thomas A LaVeist
L Ebony Boulware

Funding

Institute for Clinical and Translational Research (UL1)UL1RR025005 · NCRR · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2007 to 2011
$75.8M
Residential Segregation and Health Care Disparities P60MD000214 · NIMHD · JOHNS HOPKINS UNIVERSITY · PI LAVEIST, THOMAS ALEXIS · 2002 to 2016
$16.8M
Institute for Clinical and Translational Research (KL2)KL2RR025006 · NCRR · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2007 to 2011
$12.9M
PATIENT ORIENTED RESEARCH IN KIDNEY DISEASEK24DK002643 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI POWE, NEIL R. · 1999 to 2009
$1.4M
Clinical and Behavioral Determinants of CKD DisparitiesK23DK070757 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI BOULWARE, LEIGH E · 2006 to 2010
$724k
Trajectories of Trust Among Patients with Sickle Cell DiseaseK01HL108832 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI HAYWOOD, CARLTON · 2011 to 2014
$545k
Financial Risks and Ethnic/Racial Disparities in Live Kidney DonationF31DK084840 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI PURNELL, TANJALA · 2009 to 2011
$119k
NCRR NIH HHS 5KL2RR025006-04NCRR NIH HHS KL2 RR025006NCRR NIH HHS UL1 RR025005NCRR NIH HHS UL1RR025005NHLBI NIH HHS K01 HL108832NIDDK NIH HHS F31 DK084840NIDDK NIH HHS F31DK084840NIDDK NIH HHS K23 DK070757NIDDK NIH HHS K23DK070757NIDDK NIH HHS K24 DK002643NIDDK NIH HHS K24DK02643NIMHD NIH HHS P60 MD000214NIMHD NIH HHS P60MD000214
6 · The paper itself

Abstract

backgroundReasons for US racial-ethnic minority ESRD patients' reported difficulties identifying live kidney donors are poorly understood.

methodsWe conducted a national study to develop scales measuring willingness to donate live kidneys among US adults (scores ranged from 0 [not willing] to 10 [extremely willing]), and we tested whether racial-ethnic differences exist in willingness to donate. We also examined whether clinical, sociodemographic, and attitudinal factors mediated potential racial-ethnic differences in willingness.

resultsAmong 845 participants, the majority were extremely willing to donate to relatives (77%) while fewer than half were extremely willing to donate to non-relatives (18%). In multivariable linear regression analyses, willingness to donate varied by race-ethnicity and recipient relationship to the donor. African Americans were less willing to donate to relatives than whites (β: -0.48; 95% CI [Confidence Interval]: -0.94 to -0.17; p = 0.04), but these differences were eliminated after accounting for socioeconomic factors, medical trust, and concerns about burial after death. There were no differences in willingness to donate between Hispanics and whites.

conclusionsAfrican Americans' burial concerns, medical trust, and socioeconomic factors explained differences in their willingness to donate to relatives, suggesting efforts to address these barriers may enhance rates of live kidney donation in this group.

Indexed as

Attitude to HealthAdolescentAdultAgedBlack or African AmericanCross-Sectional StudiesFemaleHealth Knowledge, Attitudes, PracticeHispanic or LatinoHumansKidney TransplantationLiving DonorsMaleMiddle AgedPrognosisRacial Groupslive donor kidney transplantationlive kidney donationminority donationracial-ethnic disparitieswillingness to donate live kidneys

Identifiers

PMID23902226
PMCPMC3795987

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.