Evidence map›Paper›PMID 23901903›Full record

ArticleOrganic letters2013

Atom economical, one-pot, three-reaction cascade to novel tricyclic 2,4-dihydro-1H-benzo[f]isochromenes.

Robert J Hinkle, Shane E Lewis

Abstract read
In one paragraph

Article in Organic letters, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Robert J HinkleDepartment of Chemistry, The College of William & Mary, P.O. Box 8795, Williamsburg, Virginia 23187-8795, USA. rjhink@wm.edu
Shane E Lewis

Funding

Bi(III)-Initiated Chemistry: Mechanistic Investigations of Catalytic ActivityR15GM072525 · NIGMS · COLLEGE OF WILLIAM AND MARY · PI HINKLE, ROBERT J · 2007 to 2007
$212k
NIGMS NIH HHS R15 GM072525PHS HHS RGM072525-01A2
6 · The paper itself

Abstract

Reaction of 6-methyl-1-phenylhept-3-yne-2,6-diol with various aldehydes under Lewis acid conditions provides an atom economical, two-component cascade reaction sequence to novel 2,4-dihydro-1H-benzo[f]isochromene compounds. Aliphatic aldehydes as well as electron-deficient and -rich aromatic aldehydes can be used.

Indexed as

AldehydesAntidepressive Agents, TricyclicBenzopyransCatalysisCrystallography, X-RayLewis AcidsMolecular Structure2,4-dihydro-1H-benzo(f)isochromeneAldehydesAntidepressive Agents, TricyclicBenzopyransLewis Acids

Identifiers

PMID23901903
PMCPMC4447333

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.