ArticleThe Journal of infectious diseases2013
Serotype-specific effect of influenza on adult invasive pneumococcal pneumonia.
Article in The Journal of infectious diseases, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
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Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.
- Systematic review on serotypes distribution of pneumococcal pneumonia in adults and the elderly.BMC public health · 2025Pooled it
- Association of seasonal viral acute respiratory infection with pneumococcal disease: a systematic review of population-based studies.BMJ open · 2018Pooled it
- What is driving the resurgence and persistence of vaccine-targeted pneumococcal serotypes?-Serotype 19F as the paradigm.PLoS pathogens · 2026Review
- A dynamic transmission model for assessing the impact of pneumococcal vaccination in the United States.PloS one · 2025Article
- Effects of pneumococcal conjugate vaccines on reducing the risk of respiratory disease associated with coronavirus infection.Pneumonia (Nathan Qld.) · 2023Review
- Association of Nonpharmaceutical Interventions During the COVID-19 Pandemic With Invasive Pneumococcal Disease, Pneumococcal Carriage, and Respiratory Viral Infections Among Children in France.JAMA network open · 2022Article
- Prevention of Coronavirus Disease 2019 Among Older Adults Receiving Pneumococcal Conjugate Vaccine Suggests Interactions Between Streptococcus pneumoniae and Severe Acute Respiratory Syndrome Coronavirus 2 in the Respiratory Tract.The Journal of infectious diseases · 2022Article
- Influenza Infection Induces Alveolar Macrophage Dysfunction and Thereby Enables NoninvasiveJournal of immunology (Baltimore, Md. : 1950) · 2020Article
- Invasive Pneumococcal Disease and Influenza Activity in a Pediatric Population: Impact of PCV13 Vaccination in Pandemic and Nonpandemic Influenza Periods.Journal of clinical microbiology · 2019Article
- IL-1 Signaling Prevents Alveolar Macrophage Depletion during Influenza andJournal of immunology (Baltimore, Md. : 1950) · 2018Article
- Influenza interaction with cocirculating pathogens and its impact on surveillance, pathogenesis, and epidemic profile: A key role for mathematical modelling.PLoS pathogens · 2018Review
- Temporal cross-correlation between influenza-like illnesses and invasive pneumococcal disease in The Netherlands.Influenza and other respiratory viruses · 2017Article
- Observational
- Nasopharyngeal carriage of Streptococcus pneumoniae among children in an urban setting in Brazil prior to PCV10 introduction.Vaccine · 2016Article
- Using winter 2009-2010 to assess the accuracy of methods which estimate influenza-related morbidity and mortality.Epidemiology and infection · 2015Article
- Impact of influenza season and environmental factors on the clinical presentation and outcome of invasive pneumococcal disease.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2015Observational
- Challenges of using molecular serotyping for surveillance of pneumococcal disease.Journal of clinical microbiology · 2014Article
- Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundInfluenza affects host susceptibility to pneumococcus. We sought to evaluate whether this relationship varies by pneumococcal serotype using a large epidemiological database covering 3 decades.
methodsWeekly rates of invasive pneumococcal pneumonia (IPP) were obtained from the Danish National Laboratory Surveillance System, and influenza-like illness (ILI) data were collected from Danish sentinel surveillance, Statens Serum Institut, 1977-2007. We fit Poisson regression models for each age and comorbidity group, with predictors for seasonality and secular changes, ILI activity, and serotype.
resultsAmong individuals with low levels of comorbidities, influenza had the largest impact on IPP incidence among low-invasiveness serotypes (influenza attributable percent: 17.9%, 95% confidence interval [CI], 13.6-21.9) as compared with high-invasiveness serotypes (6.7%, 95% CI, 3.8%-11.7%). Among those with higher levels of comorbidities, the effect of influenza was smaller, but high-invasiveness serotypes increased more than low-invasiveness serotypes (8.9% [95% CI, 6.6-11.8] vs. 1.3% [95% CI, -1.6-5.4].
conclusionsInfluenza was associated with the greatest increases in the incidence of disease caused by serotypes with lower invasive potential and among individuals with low levels of comorbid conditions. The importance of influenza for adult IPP varies by serotype and host comorbidity.
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