Evidence map›Paper›PMID 23900919›Full record

ArticleChembiochem : a European journal of chemical biology2013

A single-stranded junction modulates nanosecond motional ordering of the substrate recognition duplex of a group I ribozyme.

Phuong Nguyen, Xuesong Shi, Snorri Th Sigurdsson, Daniel Herschlag, Peter Z Qin

Abstract read
In one paragraph

Article in Chembiochem : a European journal of chemical biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Phuong NguyenDepartment of Chemistry, University of Southern California, LJS-251, 840 Downey Way, Los Angeles, CA 90089-0744 (USA) http://pzqin.usc.edu/pzqhome.
Xuesong Shi
Snorri Th Sigurdsson
Daniel Herschlag
Peter Z Qin

Funding

Time-resolved small angle X-ray scatteringP01GM066275 · NIGMS · STANFORD UNIVERSITY · PI HERSCHLAG, DANIEL · 2003 to 2017
$17.8M
ENZYMOLOGY OF A CATALYTIC RNA MOLECULER01GM049243 · NIGMS · STANFORD UNIVERSITY · PI HERSCHLAG, DANIEL · 1993 to 2016
$2.3M
Structure, dynamics, and function of the packaging RNAR01GM069557 · NIGMS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI QIN, PETER Z · 2006 to 2010
$1.4M
NIGMS NIH HHS P01 GM066275NIGMS NIH HHS P01GM66275NIGMS NIH HHS R01 GM049243NIGMS NIH HHS R01 GM069557NIGMS NIH HHS R01GM069557
6 · The paper itself

Abstract

Rigid spinning: Site-directed spin-labeling studies using a rigid nitroxide spin label (Ç) reveal that both length and sequence of a single-stranded junction (J1/2) modulate nanosecond motional ordering of the substrate-recognition duplex (P1) of the 120 kD group I ribozyme. The studies demonstrate an approach for experimental measurements of nanosecond dynamics in high-molecular-weight RNA complexes.

Indexed as

Electron Spin Resonance SpectroscopyRNARNA, CatalyticSpin LabelsSubstrate SpecificityTetrahymenaTime FactorsGIR1 ribozymeRNARNA, CatalyticSpin LabelsdynamicsEPR spectroscopymotional orderingRNAspin labeling

Identifiers

PMID23900919
PMCPMC3817310

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.