ArticleThe European journal of health economics : HEPAC : health economics in prevention and care2013
Time trade-off: one methodology, different methods.
Article in The European journal of health economics : HEPAC : health economics in prevention and care, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 80 papers, 6 of them syntheses that pooled it.
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Who cites it
80 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- The Use of EQ-5D in the Middle East and North Africa Region: A Systematic Literature Review.PharmacoEconomics · 2025Pooled it
- Time trade-off health state utility values for depression: a systematic review and meta-analysis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023Pooled it
- Patient choice in colorectal cancer treatment - A systematic review and narrative synthesis of attribute-based stated preference studies.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2022Pooled it
- Discrete choice experiments to generate utility values for multi-attribute utility instruments: a systematic review of methods.The European journal of health economics : HEPAC : health economics in prevention and care · 2020Pooled it
- A systematic literature review of health state utility values in head and neck cancer.Health and quality of life outcomes · 2017Pooled it
- Health State Preference Weights for the Glasgow Outcome Scale Following Traumatic Brain Injury: A Systematic Review and Mapping Study.Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research · 2017Pooled it
- Is episodic future thinking effective in mitigating the influence of time preference in time trade-off?The European journal of health economics : HEPAC : health economics in prevention and care · 2025Trial
- Do we agree on health state outcomes? A review of measurement agreement between time-trade off and other utility measures.The European journal of health economics : HEPAC : health economics in prevention and care · 2026Article
- Estimating the Impact of Hemophilia A Treatment Administration on Patient Health Utility: Combining a Discrete Choice Experiment with Time Trade-Off Method.Advances in therapy · 2026Article
- Reliability and validity of EuroQol-5 Dimensions-5 Levels in patients with haematologic malignancies: a cross-sectional study in China.BMJ open · 2026Observational
- Article
- Deploying Experienced Utility in Health Economic Evaluation: A Quantitative Study.Journal of market access & health policy · 2025Article
- Comparing EQ-5D-5L, PROPr, SF-6D and TTO utilities in patients with chronic skin diseases.The European journal of health economics : HEPAC : health economics in prevention and care · 2025Article
- Deploying the Substitutive and Complementary Approaches to Enhance Predictions of Health Behaviour in Health Economics: A Quantitative Study.Healthcare (Basel, Switzerland) · 2025Article
- Health State Utilities Associated With Treatment Burden in Cystic Fibrosis: A Patient Valuation Study.CHEST pulmonary · 2025Article
- Estimating health state utilities for aromatic L-amino acid decarboxylase deficiency (AADCd) in the United States.Health and quality of life outcomes · 2025Article
- Comparison of health-related quality of life in atopic dermatitis, hidradenitis suppurativa, pemphigus and psoriasis.Archives of dermatological research · 2025Article
- Developing a Process for Preference Measures in Pediatric Growth Hormone Deficiency: Challenges and Solutions.Patient preference and adherence · 2025Article
- Estimation of Health State Utility Values for Immunoglobulin A Nephropathy: A Time Trade-Off Analysis.PharmacoEconomics - open · 2025Article
- The health-related quality of life in patients with dry eye syndrome: a cross-sectional study in Thailand.BMC ophthalmology · 2024Article
20 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There is no scientific consensus on the optimal specification of the time trade-off (TTO) task. As a consequence, studies using TTO to value health states may share the core element of trading length of life for quality of life, but can differ considerably on many other elements. While this pluriformity in specifications advances the understanding of TTO from a methodological point of view, it also results in incomparable health state values. Health state values are applied in health technology assessments, and in that context comparability of information is desired. In this article, we discuss several alternative specifications of TTO presented in the literature. The defining elements of these specifications are identified as being either methodological, procedural or analytical in nature. Where possible, it is indicated how these elements affect health state values (i.e., upward or downward). Finally, a checklist for TTO studies is presented, which incorporates a list of choices to be made by researchers who wish to perform a TTO task. Such a checklist enables other researchers to align methodologies in order to enhance the comparability of health state values.
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