ArticleMedicine and science in sports and exercise2014
Cardiovagal modulation and efficacy of aerobic exercise training in obese individuals.
Article in Medicine and science in sports and exercise, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
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Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Physical Exercise Improves Heart Rate Variability in Patients with Type 2 Diabetes: A Systematic Review.Current diabetes reports · 2017Pooled it
- Individual exercise training response and ECG morphology in patients after an acute coronary syndrome.Physiological reports · 2025Article
- Cardiac Autonomic Modulation in Response to Three Types of Exercise in Patients with Type 2 Diabetic Neuropathy.Journal of diabetes and metabolic disorders · 2021Article
- Noninvasive assessment of autonomic modulation of heart rate variability in the Ts65Dn mouse model of Down syndrome: A proof of principle study.Physiological reports · 2020Article
- Determination of the Maximal Lactate Steady State by HRV in Overweight and Obese Subjects.Sports medicine international open · 2019Article
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Authors and funding
5 authors.
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Abstract
unlabelledType 2 diabetes (T2D) is associated with poor exercise tolerance and peak aerobic capacity (V˙O2peak) even when compared to obese nondiabetic peers. Exercise training studies have demonstrated improvements in V˙O2peak among patients with T2D, yet there is a large amount of variability in this response. Recent evidence suggests that cardiac autonomic modulation may be an important factor when considering improvements in aerobic capacity. PURPOSE: This study aimed to determine the effects of a 16-wk aerobic exercise program on V˙O2peak in obese individuals, with and without T2D, who were classified as having either high or low cardiovagal modulation (HCVM or LCVM) at baseline.
methodsObese individuals (38 women and 19 men; body mass index = 36.1 kg·m(-2)) were studied in the fasted state. ECG recordings were obtained while seated for 3 min, before and after 4 months of exercise training (4 d·wk(-1), 65% V˙O(2peak)). The ECG recording was analyzed for HR variability in the spectral domain. Groups were split on a marker of CVM (normalized high frequency (HFnu)) at the 50th percentile, as either HCVM or LCVM.
resultsV˙O(2peak) only increased with exercise training among those classified as having HCVM, regardless of diabetes status (T2D: HCVM = 20.3-22.5 mL·kg(-1)min(-1), LCVM = 24.3-25.0 mL·kg(-1)min(-1); obese nondiabetics: HCVM = 24.5-26.3 mL·kg(-1)min(-1), LCVM = 23.1-23.7 mL·kg(-1)min(-1)) (P < 0.05). No change in V˙O(2peak) was observed for the LCVM group. Changes in weight do not explain the change in V˙O(2peak) among the HCVM group. Glucose tolerance only improved among the LCVM group with T2D.
conclusionsObese individuals, with or without T2D, when classified as having relatively HCVM before exercise training, have a greater propensity to improve V˙O(2peak) after a 16-wk aerobic training program.
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