ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2013
Effect of nucleic acid amplification testing on population-based incidence rates of Clostridium difficile infection.
Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
48 citing papers in PubMed, 3 syntheses or guidelines pooled it, 105 citations in OpenAlex.
- Clinical significance of toxin EIA positivity in patients with suspectedJournal of clinical microbiology · 2025Pooled it
- Global burden ofJournal of global health · 2019Pooled it
- Clinical Practice Guidelines for Clostridium difficile Infection in Adults and Children: 2017 Update by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA).Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2018Guideline
- Attributable Costs ofJournal of Korean medical science · 2025Article
- Three stages of laboratory stewardship in improving appropriateAntimicrobial stewardship & healthcare epidemiology : ASHE · 2025Article
- Potential underreporting of treated patients using aInfection control and hospital epidemiology · 2024Observational
- Incidence ofJournal of Korean medical science · 2024Observational
- Use of electronic health record data to identify hospital-associatedmedRxiv : the preprint server for health sciences · 2024Article
- The changing epidemiology ofAntimicrobial stewardship & healthcare epidemiology : ASHE · 2024Article
- A Rare Case of Polymerase Chain Reaction-Negative Severe Clostridioides difficile Infection.Cureus · 2023Article
- Laboratory diagnosis of Clostridioides difficile infection in symptomatic patients: what can we do better?Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2023Article
- Trends inAnnals of medicine · 2022Article
- A Baker's Dozen of Top Antimicrobial Stewardship Intervention Publications for Hospitalized Patients in 2021.Open forum infectious diseases · 2022Review
- Treatment and Outcomes ofJournal of clinical medicine · 2022Article
- Clinical Outcomes of Treated and Untreated C. difficile PCR-Positive/Toxin-Negative Adult Hospitalized Patients: a Quasi-Experimental Noninferiority Study.Journal of clinical microbiology · 2022Article
- Incidence and Outcomes Associated With Clostridioides difficile Infection in Solid Organ Transplant Recipients.JAMA network open · 2021Article
- Correlation between antibiotic consumption and the incidence of healthcare facility-onset Clostridioides difficile infection: a retrospective chart review and analysis.Antimicrobial resistance and infection control · 2021Article
- Changing Results to Change Results: Nudging Antimicrobial Prescribing forOpen forum infectious diseases · 2021Article
- Review
- Antibiotic Resistances and Molecular Characteristics ofFrontiers in medicine · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 7 institutions in 2 countries.
Funding
Abstract
Nucleic acid amplification testing (NAAT) is increasingly being adopted for diagnosis of Clostridium difficile infection (CDI). Data from 3 states conducting population-based CDI surveillance showed increases ranging from 43% to 67% in CDI incidence attributable to changing from toxin enzyme immunoassays to NAAT. CDI surveillance requires adjustment for testing methods.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.