Evidence map›Paper›PMID 23898373›Full record

ArticleWorld journal of hepatology2013

Hepatitis C virus genotypes in north eastern Algeria: A retrospective study.

Samir Rouabhia, Mourad Sadelaoud, Karima Chaabna-Mokrane, Wided Toumi, Ludovico Abenavoli

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Article in World journal of hepatology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Samir RouabhiaSamir Rouabhia, Department of Internal Medicine, University Hospital Center Touhami Benfis, Batna 05000, Algeria.
Mourad Sadelaoud
Karima Chaabna-Mokrane
Wided Toumi
Ludovico Abenavoli
University of Batna 1 · DZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo determine the frequency of various hepatitis C virus (HCV) genotypes present in patients from north eastern Algeria.

methodsThis is a retrospective cross-sectional study of 435 HCV infected patients from northeast Algeria, detected in the Sadelaoud laboratory and diagnosed between January 2010 and December 2012. The patients were diagnosed with HCV infection in their local hospitals and referred to be assessed for HCV genotype before the antiviral treatment. Demographic information (sex, age and address), genotype, subtype and viral load were retrieved from the patient medical records. The serum samples were tested by the type-specific genotyping assay.

resultsThe majority of the patients (82.5%) were from the central part of the examined region (P = 0.002). The mean age of the patients studied was 53.6 ± 11.5 years. HCV genotype 1 was the most frequent (88.7%), followed by genotypes 2 (8.5%), 4 (1.1%), 3 (0.9%) and 5 (0.2%). Genotype 6 was not detected in these patients. Mixed infection across the HCV subtypes was detected in twenty patients (4.6%). The genotype distribution was related to age and region. Genotype 1 was significantly less frequent in the ≥ 60 age group than in the younger age group (OR = 0.2; 95%CI: 0.1-0.5, P < 0.001). Furthermore, genotype 1 was more frequent in the central part of the examined region than elsewhere (P < 0.01).

conclusionThe HCV genotype (type 1b was dominant) distribution in Algeria is different from those in other northern countries of Africa.

Indexed as

AlgeriaGenotype 1bHepatitis C virusPrevalenceViral load

Identifiers

PMID23898373
PMCPMC3724968
OpenAlexW1993510704

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.