ArticleFrontiers in human neuroscience2013
Altered visual information processing systems in bipolar disorder: evidence from visual MMN and P3.
Article in Frontiers in human neuroscience, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.
- Pooled it
- Schizophrenia disrupts normative covariation of neural activity across modalities of perception.Journal of psychopathology and clinical science · 2026Article
- Attention is required for canonical brain signature of prediction error despite early encoding of the stimuli.PLoS biology · 2023Article
- Emotion regulation in bipolar disorder type-I: multivariate analysis of fMRI data.International journal of bipolar disorders · 2023Article
- Segregation, integration and balance in resting-state brain functional networks associated with bipolar disorder symptoms.Human brain mapping · 2023Article
- MICEmi: A method to identify cognitive endophenotypes of mental illnesses.European psychiatry : the journal of the Association of European Psychiatrists · 2022Review
- A Possible Trait and Status Marker in Bipolar Disorder: The Electroretinogram-Pattern.Actas espanolas de psiquiatria · 2022Article
- Event-related potentials to rare visual targets and negative symptom severity in a transdiagnostic psychiatric sample.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2021Article
- Reduced influence of perceptual context in schizophrenia: behavioral and neurophysiological evidence.Psychological medicine · 2021Article
- Deficits in Auditory and Visual Sensory Discrimination Reflect a Genetic Liability for Psychosis and Predict Disruptions in Global Cognitive Functioning.Frontiers in psychiatry · 2020Article
- Neural anomalies during vigilance in schizophrenia: Diagnostic specificity and genetic associations.NeuroImage. Clinical · 2020Article
- Transdiagnostic Multimodal Neuroimaging in Psychosis: Structural, Resting-State, and Task Magnetic Resonance Imaging Correlates of Cognitive Control.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2019Article
- Shared and Disorder-Specific Event-Related Brain Oscillatory Markers of Attentional Dysfunction in ADHD and Bipolar Disorder.Brain topography · 2018Article
- Automatic detection advantage of network information among Internet addicts: behavioral and ERP evidence.Scientific reports · 2018Article
- Automatic Processing of Changes in Facial Emotions in Dysphoria: A Magnetoencephalography Study.Frontiers in human neuroscience · 2018Article
- Disorder-specific and shared neurophysiological impairments of attention and inhibition in women with attention-deficit/hyperactivity disorder and women with bipolar disorder.Psychological medicine · 2016Article
- Visual mismatch negativity (vMMN): a prediction error signal in the visual modality.Frontiers in human neuroscience · 2014Article
- Visual mismatch negativity: a predictive coding view.Frontiers in human neuroscience · 2014Review
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveMismatch negativity (MMN) and P3 are unique ERP components that provide objective indices of human cognitive functions such as short-term memory and prediction. Bipolar disorder (BD) is an endogenous psychiatric disorder characterized by extreme shifts in mood, energy, and ability to function socially. BD patients usually show cognitive dysfunction, and the goal of this study was to access their altered visual information processing via visual MMN (vMMN) and P3 using windmill pattern stimuli.
methodsTwenty patients with BD and 20 healthy controls matched for age, gender, and handedness participated in this study. Subjects were seated in front of a monitor and listened to a story via earphones. Two types of windmill patterns (standard and deviant) and white circle (target) stimuli were randomly presented on the monitor. All stimuli were presented in random order at 200-ms durations with an 800-ms inter-stimulus interval. Stimuli were presented at 80% (standard), 10% (deviant), and 10% (target) probabilities. The participants were instructed to attend to the story and press a button as soon as possible when the target stimuli were presented. Event-related potentials (ERPs) were recorded throughout the experiment using 128-channel EEG equipment. vMMN was obtained by subtracting standard from deviant stimuli responses, and P3 was evoked from the target stimulus.
resultsMean reaction times for target stimuli in the BD group were significantly higher than those in the control group. Additionally, mean vMMN-amplitudes and peak P3-amplitudes were significantly lower in the BD group than in controls.
conclusionsAbnormal vMMN and P3 in patients indicate a deficit of visual information processing in BD, which is consistent with their increased reaction time to visual target stimuli. SIGNIFICANCE: Both bottom-up and top-down visual information processing are likely altered in BD.
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