ArticleThe Plant cell2013
Infection structure-specific expression of β-1,3-glucan synthase is essential for pathogenicity of Colletotrichum graminicola and evasion of β-glucan-triggered immunity in maize.
Article in The Plant cell, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 94 citations in OpenAlex.
- Lysin Motif Effectors Facilitate the Endophytic Colonization of Wheat by Sclerotinia sclerotiorum via Modulating Plant Immunity.Molecular plant pathology · 2026Article
- Genomic insights into the broad-spectrum antifungal activity of a novel Paenibacillus polymyxa strain X-11.BMC microbiology · 2026Article
- Global mRNA profiling reveals the effect of boron as a crop protection tool againstAoB PLANTS · 2024Article
- Glucanases and Chitinases inMolecules (Basel, Switzerland) · 2024Article
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- Molecular Characterization of Germin-like Protein Genes inACS omega · 2023Article
- The Small Ras Superfamily GTPase Rho4 of the Maize Anthracnose FungusJournal of fungi (Basel, Switzerland) · 2022Article
- Sandwich Enzyme-Linked Immunosorbent Assay for Quantification of Callose.Methods and protocols · 2022Article
- Fungal Pathogenesis-Related Cell Wall Biogenesis, with Emphasis on the Maize Anthracnose FungusPlants (Basel, Switzerland) · 2022Review
- SsAGM1-Mediated Uridine Diphosphate-Frontiers in microbiology · 2022Article
- Secreted Glycoside Hydrolase Proteins as Effectors and Invasion Patterns of Plant-Associated Fungi and Oomycetes.Frontiers in plant science · 2022Review
- Genome-Wide Association Studies Identifying Multiple Loci Associated With Alfalfa Forage Quality.Frontiers in plant science · 2021Article
- Phytohormones (Auxin, Gibberellin) and ACC Deaminase In Vitro Synthesized by the MycoparasiticInternational journal of molecular sciences · 2019Article
- The MAP Kinase CfPMK1 Is a Key Regulator of Pathogenesis, Development, and Stress Tolerance ofFrontiers in microbiology · 2019Article
- Article
- Comparative transcriptomic analysis indicates genes associated with local and systemic resistance to Colletotrichum graminicola in maize.Scientific reports · 2017Article
- The Fungal Cell Wall: Structure, Biosynthesis, and Function.Microbiology spectrum · 2017Review
- The fungal-specific β-glucan-binding lectin FGB1 alters cell-wall composition and suppresses glucan-triggered immunity in plants.Nature communications · 2016Article
- An RNAi-Based Control of Fusarium graminearum Infections Through Spraying of Long dsRNAs Involves a Plant Passage and Is Controlled by the Fungal Silencing Machinery.PLoS pathogens · 2016Article
- Host-induced silencing of Fusarium culmorum genes protects wheat from infection.Journal of experimental botany · 2016Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
β-1,3-Glucan and chitin are the most prominent polysaccharides of the fungal cell wall. Covalently linked, these polymers form a scaffold that determines the form and properties of vegetative and pathogenic hyphae. While the role of chitin in plant infection is well understood, the role of β-1,3-glucan is unknown. We functionally characterized the β-1,3-glucan synthase gene GLS1 of the maize (Zea mays) pathogen Colletotrichum graminicola, employing RNA interference (RNAi), GLS1 overexpression, live-cell imaging, and aniline blue fluorochrome staining. This hemibiotroph sequentially differentiates a melanized appressorium on the cuticle and biotrophic and necrotrophic hyphae in its host. Massive β-1,3-glucan contents were detected in cell walls of appressoria and necrotrophic hyphae. Unexpectedly, GLS1 expression and β-1,3-glucan contents were drastically reduced during biotrophic development. In appressoria of RNAi strains, downregulation of β-1,3-glucan synthesis increased cell wall elasticity, and the appressoria exploded. While the shape of biotrophic hyphae was unaffected in RNAi strains, necrotrophic hyphae showed severe distortions. Constitutive expression of GLS1 led to exposure of β-1,3-glucan on biotrophic hyphae, massive induction of broad-spectrum defense responses, and significantly reduced disease symptom severity. Thus, while β-1,3-glucan synthesis is required for cell wall rigidity in appressoria and fast-growing necrotrophic hyphae, its rigorous downregulation during biotrophic development represents a strategy for evading β-glucan-triggered immunity.
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