Evidence map›Paper›PMID 23897505›Full record

ArticleClinical orthopaedics and related research2014

Continuous adductor canal blocks are superior to continuous femoral nerve blocks in promoting early ambulation after TKA.

Seshadri C Mudumbai, T Edward Kim, Steven K Howard, J Justin Workman, Nicholas Giori, Steven Woolson, Toni Ganaway, Robert King, Edward R Mariano

4 registry-linked trialsAbstract readComparative Study
In one paragraph

Article in Clinical orthopaedics and related research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 48 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 7 pooled it
15.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02121392 nacompletednot on this map

Continuous Adductor Canal Block With Epidural Analgesia for Total Knee Arthroplasty: A Prospective, Randomized, Double-blinded, Placebo-Controlled Trial

TypeinterventionalSponsorUniversity of ChicagoRan2014 to 2017Enrolled165ConditionsArthroplasty, Replacement, Knee, Nerve BlockArmsAdductor Canal Nerve Block Catheter, Adductor Canal Nerve Block Sham Catheter, Bupivacaine
NCT02276495 nacompletednot on this mapstarted 2015, after this paper: background citation

Does Single Injection Adductor Canal Block Improve Postoperative Analgesia in Patients Receiving Periarticular Local Anesthesia Injections for Total Knee Arthroplasty?

TypeinterventionalSponsorUniversity of California, IrvineRan2015 to 2024Enrolled55ConditionsPain ManagementArmsACB Control - 20 ml saline injection for ACB, ACB Study - 20 ml 0.5% Ropivacaine for Adductor Canal Block, Local infiltration - 100 mLs of a solution containing: Ropivacaine + Epinephrine + Ketorolac + Clonidine + 0.9% Normal saline
NCT02581683 phase4completednot on this mapstarted 2015, after this paper: background citation

Does Magnesium Sulfate as a Supplement in Adductor Canal Blocks Improve Pain Control After Total Knee Arthroplasty?

TypeinterventionalSponsorQueen's UniversityRan2015 to 2017Enrolled130ConditionsKnee ArthroplastyArmsMagnesium Sulfate, Ropivacaine, Sham
NCT02584452 nacompletednot on this mapstarted 2015, after this paper: background citation

Randomized Controlled Trial Evaluating Postoperative Analgesia and Muscle Strength Between Single Versus Continuous Adductor Canal Block for Ambulatory ACL Reconstruction.

TypeinterventionalSponsorVanderbilt University Medical CenterRan2015 to 2018Enrolled59ConditionsRupture of Anterior Cruciate Ligament, Tear of Anterior Cruciate LigamentArmsMepivacaine, adductor canal continuous nerve catheter, Normal Saline as bolus followed by bupivacaine, adductor canal nerve block, ropivacaine and dexamethasone
3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 7 syntheses or guidelines pooled it, 139 citations in OpenAlex.

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  4. Meta-analysis of epidural analgesia versus peripheral nerve blockade after total knee joint replacement.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2017
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  19. [Research progress on analgesic effect of adductor canal block after knee arthroplasty].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Seshadri C MudumbaiDepartment of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford, CA, USA.
T Edward Kim
Steven K Howard
J Justin Workman
Nicholas Giori
Steven Woolson
Toni Ganaway
Robert King
Edward R Mariano
Stanford University · USS.P.E.C.I.E.S. · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFemoral continuous peripheral nerve blocks (CPNBs) provide effective analgesia after TKA but have been associated with quadriceps weakness and delayed ambulation. A promising alternative is adductor canal CPNB that delivers a primarily sensory blockade; however, the differential effects of these two techniques on functional outcomes after TKA are not well established. QUESTIONS/PURPOSES: We determined whether, after TKA, patients with adductor canal CPNB versus patients with femoral CPNB demonstrated (1) greater total ambulation distance on Postoperative Day (POD) 1 and 2 and (2) decreased daily opioid consumption, pain scores, and hospital length of stay.

methodsBetween October 2011 and October 2012, 180 patients underwent primary TKA at our practice site, of whom 93% (n = 168) had CPNBs. In this sequential series, the first 102 patients had femoral CPNBs, and the next 66 had adductor canal CPNBs. The change resulted from a modification to our clinical pathway, which involved only a change to the block. An evaluator not involved in the patients' care reviewed their medical records to record the parameters noted above.

resultsAmbulation distances were higher in the adductor canal group than in the femoral group on POD 1 (median [10(th)-90(th) percentiles]: 37 m [0-90 m] versus 6 m [0-51 m]; p < 0.001) and POD 2 (60 m [0-120 m] versus 21 m [0-78 m]; p = 0.003). Adjusted linear regression confirmed the association between adductor canal catheter use and ambulation distance on POD 1 (B = 23; 95% CI = 14-33; p < 0.001) and POD 2 (B = 19; 95% CI = 5-33; p = 0.008). Pain scores, daily opioid consumption, and hospital length of stay were similar between groups.

conclusionsAdductor canal CPNB may promote greater early postoperative ambulation compared to femoral CPNB after TKA without a reduction in analgesia. Future randomized studies are needed to validate our major findings. LEVEL OF EVIDENCE: Level III, therapeutic study. See Instructions for Authors for a complete description of levels of evidence.

Indexed as

Arthroplasty, Replacement, KneeEarly AmbulationFemoral NerveAgedAnalgesics, OpioidAnalysis of VarianceFemaleHumansLength of StayLinear ModelsMaleMiddle AgedNerve BlockPain MeasurementPostoperative PainRetrospective StudiesAnalgesics, Opioid

Identifiers

PMID23897505
PMCPMC3971247
OpenAlexW2119068199

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.