ArticleThe Journal of comparative neurology2014
Morphology and ultrastructure of medial rectus subgroup motoneurons in the macaque monkey.
Article in The Journal of comparative neurology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
27 citing papers in PubMed, 32 citations in OpenAlex.
- Neural Innervation of Cyclovertical Extraocular Muscles During Asymmetric Vertical Vergence.Investigative ophthalmology & visual science · 2026Article
- Neural Control of Vergence and Ocular Accommodation.Annual review of vision science · 2025Review
- Subsets of extraocular motoneurons produce kinematically distinct saccades during hunting and exploration.Current biology : CB · 2025Article
- Ion channel profiles of extraocular motoneurons and internuclear neurons in human abducens and trochlear nuclei.Frontiers in neuroanatomy · 2024Article
- Investigation of Selective Innervation of Extraocular Muscle Compartments.Investigative ophthalmology & visual science · 2023Article
- Is the central mesencephalic reticular formation a purely horizontal gaze center?Brain structure & function · 2022Article
- Extraocular Motoneurons and Neurotrophism.Advances in neurobiology · 2022Article
- MIF versus SIF Motoneurons, What Are Their Respective Contribution in the Oculomotor Medial Rectus Pool?The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Macaque monkey trigeminal blink reflex circuits targeting levator palpebrae superioris motoneurons.The Journal of comparative neurology · 2021Article
- Transmitter and ion channel profiles of neurons in the primate abducens and trochlear nuclei.Brain structure & function · 2021Article
- Cerebellar projections to the macaque midbrain tegmentum: Possible near response connections.Visual neuroscience · 2021Article
- Botulinum toxin injection without electromyographic guidance in consecutive esotropia.PloS one · 2020Article
- Mouse Extraocular Muscles and the Musculotopic Organization of Their Innervation.Anatomical record (Hoboken, N.J. : 2007) · 2019Article
- Central mesencephalic reticular formation control of the near response: lens accommodation circuits.Journal of neurophysiology · 2019Article
- Functional diversity of motoneurons in the oculomotor system.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Transduction of Craniofacial Motoneurons Following Intramuscular Injections of Canine Adenovirus Type-2 (CAV-2) in Rhesus Macaques.Frontiers in neuroanatomy · 2019Article
- Serotonin receptor 2c-expressing cells in the ventral CA1 control attention via innervation of the Edinger-Westphal nucleus.Nature neuroscience · 2018Article
- A central mesencephalic reticular formation projection to medial rectus motoneurons supplying singly and multiply innervated extraocular muscle fibers.The Journal of comparative neurology · 2017Article
- Examination of feline extraocular motoneuron pools as a function of muscle fiber innervation type and muscle layer.The Journal of comparative neurology · 2017Article
- Ultrastructural pathological alterations in ocular muscles in a cat model with exotropia.International journal of clinical and experimental pathology · 2017Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
Abstract
There are two muscle fiber types in extraocular muscles: those receiving a single motor endplate, termed singly innervated fibers (SIFs), and those receiving multiple small terminals along their length, termed multiply innervated fibers (MIFs). In monkeys, these two fiber types receive input from different motoneuron pools: SIF motoneurons found within the extraocular motor nuclei, and MIF motoneurons found along their periphery. For the monkey medial rectus muscle, MIF motoneurons are found in the C-group, while SIF motoneurons lie in the A- and B-groups. We analyzed the somatodendritic morphology and ultrastructure of these three subgroups of macaque medial rectus motoneurons to better understand the structural determinants controlling the two muscle fiber types. The dendrites of A- and B-group motoneurons lay within the oculomotor nucleus, but those of the C-group motoneurons were located outside the nucleus, and extended into the preganglionic Edinger-Westphal nucleus. A- and B-group motoneurons were very similar ultrastructurally. In contrast, C-group motoneurons displayed significantly fewer synaptic contacts on their somata and proximal dendrites, and those contacts were smaller in size and lacked dense-cored vesicles. However, the synaptic structure of C-group distal dendrites was quite similar to that observed for A- and B-group motoneurons. Our anatomical findings suggest that C-group MIF motoneurons have different physiological properties than A- and B-group SIF motoneurons, paralleling their different muscle fiber targets. Moreover, primate C-group motoneurons have evolved a special relationship with the preganglionic Edinger-Westphal nucleus, suggesting these motoneurons play an important role in near triad convergence to support increased near work requirements.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.