Evidence map›Paper›PMID 23897006›Full record

SynthesisJournal of assisted reproduction and genetics2013

Fertility management in the PCOS population: results of a web-based survey at IVF-worldwide.com.

Paul R Brezina, Virginia Mensah, Adam Balen, Milton Leong, Ariel Weissman, Yulian Zhao, Zeev Shoham

Open access · hybridAbstract readMeta-Analysis
In one paragraph

Synthesis in Journal of assisted reproduction and genetics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.3field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 9 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 4 countries.

Paul R BrezinaReproductive Genetics, Fertility Associates of Memphis, 80 Humpreys Center, Suite 307, Memphis, TN, 38120-2363, USA, brezinamd@gmail.com.
Virginia Mensah
Adam Balen
Milton Leong
Ariel Weissman
Yulian Zhao
Zeev Shoham
Hong Kong Sanatorium and Hospital · HKJohns Hopkins Medicine · USJohns Hopkins University · USKaplan Medical Center · ILSeacroft Hospital · GBWolfson Medical Center · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo identify the leading treatment strategies for infertile women with PCOS on an international scale.

methodsA retrospective evaluation using the results of a web-based survey, (IVF-Worldwide ( www.IVF-worldwide.com ), posted from 1 to 30 September 2010 was performed. Binomial confidence intervals for proportions were calculated by the modified Wald method with significance defined as P < 0.05 using a DataStar software package (DataStar, Waltham, MA, USA). Incomplete surveys were excluded from the analysis.

resultsThe results from 262 centers in 68 nations were obtained. Clomiphene citrate was the clear first choice, 68 %, for PCOS treatment in the respondent group. Eighty-eight percent of respondents utilized ultrasound follicular monitoring when conducting ovulation induction with oral medications. A significant (p < 0.05) proportion of respondents (66 %) did use some BMI cutoff beyond which IVF treatment was not offered. The preferred IVF protocols for PCOS patients were gonadotropin releasing hormone (GnRH) antagonist, 46 %, and GnRH agonist, 51 %. There was heterogeneity of responses observed regarding the management of a patient at very high risk of OHSS.

conclusionsWhile some advances, such as the use of GnRH antagonist regimen in IVF cycles, were relatively underutilized, the survey gives an unfiltered snapshot at the practice patterns of a large number of clinics. Results from this survey may be used by researchers and professional organizations to improve the clinical care of PCOS women suffering with infertility.

Indexed as

Fertilization in VitroClomipheneFemaleGonadotropin-Releasing HormoneGonadotropinsHumansInfertility, FemaleOvulation InductionPolycystic Ovary SyndromeRetrospective StudiesSoftwareClomipheneGonadotropin-Releasing HormoneGonadotropins

Identifiers

PMID23897006
PMCPMC3800525
OpenAlexW2051370171

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.