ReviewBMC nephrology2013
The pathophysiology of hyperuricaemia and its possible relationship to cardiovascular disease, morbidity and mortality.
Review in BMC nephrology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 87 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
87 citing papers in PubMed.
- Lesinurad in combination with allopurinol: a randomised, double-blind, placebo-controlled study in patients with gout with inadequate response to standard of care (the multinational CLEAR 2 study).Annals of the rheumatic diseases · 2017Trial
- The effects of allopurinol on metabolic acidosis and endothelial functions in chronic kidney disease patients.Clinical and experimental nephrology · 2015Trial
- Combined cord blood metabolomic and clinical signatures discriminate small for gestational age neonates in preeclampsia.Frontiers in endocrinology · 2026Article
- Correlation between obesity-related indices and hyperuricemia among the elderly population in China: A cross-sectional study.Medicine · 2025Article
- Prevalence, correlates, and treatment behaviors for urolithiasis and renal colic-like pain symptoms at the population level in Poland.Scientific reports · 2025Article
- In Slico Screening and In Vitro Identification of Hyperuricemia-Inhibiting Peptides fromFoods (Basel, Switzerland) · 2025Article
- TyG-WC Index as a Superior Predictor of Hyperuricemia Risk in the Hypertensive Population: A Prospective Cohort Study.Diabetes, metabolic syndrome and obesity : targets and therapy · 2025Article
- Analysis risk factors of long-term adverse outcomes and a prediction nomogram for coronary artery disease patients underwent fractional flow reserve.International journal of medical sciences · 2025Article
- Triponderal mass index can be used as a potential tool to predict the risk of hyperuricemia in children and adolescents with obesity: a population-based study.Frontiers in nutrition · 2025Article
- The association between insulin resistance-related markers and ASCVD with hyperuricemia: results from the 2005 to 2018 National Health and Nutrition Examination Survey.Frontiers in cardiovascular medicine · 2025Article
- The Progress of Immune Cells-induced Inflammatory Response in Gout.Current pharmaceutical design · 2025Review
- Exercise and hyperuricemia: an opinion article.Annals of medicine · 2024Article
- Association between Visceral Adiposity Index and Hyperuricemia among Steelworkers: The Moderating Effects of Drinking Tea.Nutrients · 2024Article
- Review
- An Updated Review For Hyperuricemia and Gout Management; Special Focus on the Available Drug Delivery Systems and Clinical Trials.Current medicinal chemistry · 2024Review
- The Combination of Hyperuricemia and Elevated High-Sensitivity C-Reactive Protein Increased the Risk of Cardiac Conduction Block.Journal of inflammation research · 2024Article
- The Association Between Serum Uric Acid Levels and the Risk of Cognitive Dysfunction in Patients With Atrial Fibrillation.International journal of endocrinology · 2024Article
- Article
- Extract ofFood science and biotechnology · 2022Article
- The prevalence of hyperuricemia and its correlates in Zhuang nationality, Nanning, Guangxi Province.Journal of clinical laboratory analysis · 2022Article
27 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Uric acid is the end product of purine metabolism in humans. High levels are causative in gout and urolithiasis. Hyperuricaemia has also been implicated in the pathophysiology of hypertension, chronic kidney disease (CKD), congestive heart failure (CHF), the metabolic syndrome, type 2 diabetes mellitus (T2DM), and atherosclerosis, with or without cardiovascular events. This article briefly reviews uric acid metabolism and summarizes the current literature on hyperuricaemia in cardiovascular disease and related co-morbidities, and emerging treatment options.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.