ArticlePloS one2013
Most personal exposure to house dust mite aeroallergen occurs during the day.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 56 citations in OpenAlex.
- A novel ambient air sampler for detection of allergens and endotoxin.The journal of allergy and clinical immunology. Global · 2026Article
- Questionnaire for Clinical Diagnosis of House Dust Mite's Allergy Approved by Delphi Consensus.Clinical reviews in allergy & immunology · 2025Article
- Adjuvant-independent airway sensitization and infection mouse models leading to allergic asthma.Frontiers in allergy · 2024Review
- The Acari Hypothesis, IV: revisiting the role of hygiene in allergy.Frontiers in allergy · 2024Article
- Analysis of Demodex infection rate and risk factors in patients with meibomian gland dysfunction.International ophthalmology · 2023Article
- Abundance and Stability as Common Properties of Allergens.Frontiers in allergy · 2021Review
- Update on House Dust Mite Allergen Avoidance Measures for Asthma.Current allergy and asthma reports · 2020Review
- Atopic Dermatitis: Identification and Management of Complicating Factors.International journal of molecular sciences · 2020Review
- The Role of Dust Mites in Allergy.Clinical reviews in allergy & immunology · 2019Review
- Asthma and Allergies in the School Environment.Clinical reviews in allergy & immunology · 2019Review
- A reintroduction of environmental mite allergen control strategies for asthma treatment and the debate on their effectiveness.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2019Review
- Bedroom Allergen Exposure Beyond House Dust Mites.Current allergy and asthma reports · 2018Review
- Airborne protein concentration: a key metric for type 1 allergy risk assessment-in home measurement challenges and considerations.Clinical and translational allergy · 2018Article
- Article
- NIAID, NIEHS, NHLBI, and MCAN Workshop Report: The indoor environment and childhood asthma-implications for home environmental intervention in asthma prevention and management.The Journal of allergy and clinical immunology · 2017Article
- International consensus (ICON) on: clinical consequences of mite hypersensitivity, a global problem.The World Allergy Organization journal · 2017Article
- How In Vitro Assays Contribute to Allergy Diagnosis.Current allergy and asthma reports · 2016Review
- Time-Based Measurement of Personal Mite Allergen Bioaerosol Exposure over 24 Hour Periods.PloS one · 2016Article
- Introducing an environmental assessment and intervention program in inner-city schools.The Journal of allergy and clinical immunology · 2014Review
- Reply.The journal of allergy and clinical immunology. In practiceArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe bed is commonly regarded as the main site of house dust mite exposure; however this has not been directly established by continuous measurements. The objective of this study was to determine the pattern of personal exposure to mite aeroallergen over 24 hours.
methods12 adults each collected 9 sequential samples (8 during the day, mean 115 mins, and one overnight, mean 514 mins) over 24 hours using a portable air-pump (2L/min) connected to an IOM filter located on the shoulder during the day and on the bed head overnight. Samples were analysed for mite allergen Der p 1 by ELISA. Location and activity were recorded. A mixed model analysis was performed to determine exposure as a function of 14 categories of activity.
resultsPersonal aeroallergen exposure differed widely over time, both within and between subjects. The highest average exposure (1117 pg/m(3), 95% CI: 289-4314) occurred on public transport and the lowest overnight in bed (45 pg/m(3), 95% CI: 17-17), which contributed only 9.8% (95% CI: 4.4%-15.1%) of total daily exposure. Aeroallergens were not related to bed reservoirs.
conclusionThe study challenges the current paradigm that the bed is the main site of HDM exposure and instead suggests most exposure occurs in association with domestic activity and proximity to other people. Effective mite interventions, designed to improve asthma outcomes, need to first identify and then address the multiple sources of aeroallergen exposure.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.