ReviewPloS one2013
Childhood intussusception: a literature review.
Review in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03185637 (Paediatric Surgery Across Sub-Saharan Africa), which is not on this map. Cited by 157 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Paediatric Surgery Across Sub-Saharan Africa: A Multi-Centre Prospective Cohort Study
Who cites it
157 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Ultrasound-guided hydrostatic enema reduction for intussusception in children younger than 12 months: a systematic review and meta-analysis.Pediatric surgery international · 2026Pooled it
- Efficacy and safety of nonoperative management for pediatric intussusception in Sub-Saharan Africa: a systematic review and meta-analysis.Pediatric radiology · 2026Pooled it
- Prevalence and surgical outcomes of pediatric intussusception in ethiopia: a systematic review and meta-analysis.BMC surgery · 2025Pooled it
- Update on the global epidemiology of intussusception: a systematic review of incidence rates, age distributions and case-fatality ratios among children aged <5 years, before the introduction of rotavirus vaccination.International journal of epidemiology · 2019Pooled it
- Risk Factors for Recurrent Intussusception in Children: A Systematic Review and Meta-Analysis.Frontiers in pediatrics · 2019Pooled it
- Management for intussusception in children.The Cochrane database of systematic reviews · 2017Pooled it
- A comparison of the success rate of pneumatic reduction in intussusception between general anesthesia and deep sedation: a randomized controlled trial.Pediatric surgery international · 2023Trial
- Chronic intussusception revealing primary diffuse large B-cell lymphoma of the small intestine: A case report.Radiology case reports · 2026Article
- Rebound of pediatric idiopathic ileocolic intussusception following the COVID-19 pandemic: a longitudinal follow-up study.Pediatric radiology · 2026Article
- Effectiveness of ultrasound-guided hydrostatic versus fluoroscopy-guided air reduction for pediatric intussusception: a severity-adjusted cohort analysis.Pediatric surgery international · 2026Article
- [Epidemiological characteristics of intussusception in children aged 0-3 years in Jiangsu Province from 2018 to 2023].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2026Article
- A decade after introduction: survey of training and expansion of ultrasound-guided hydrostatic reduction of intussusception in Ethiopia.Emergency radiology · 2026Article
- A scoring model based on risk factors for prediction of intussusception recurrence in pediatric patients.Pediatric surgery international · 2026Article
- Multiple small bowel cavernous hemangiomas complicated with intussusception presenting with intestinal obstruction: rare case report from Sudan and literature review.International journal of surgery case reports · 2026Article
- Article
- Epidemiology and Management of Intussusception Among Children Aged Under 2 Years in Gujarat, India.Indian journal of pediatrics · 2025Article
- Epidemiological and Clinical Characteristics of Intussusception in Children Aged Under 2 Years: Comparison of the Southern and Western States in India, 2019-2022.Indian journal of pediatrics · 2025Observational
- Opioid Administration and Reduction of Pediatric Ileocolic Intussusception.JAMA network open · 2025Article
- Jejunojejunal Intussusception in an 11 year old: A Case Report.JNMA; journal of the Nepal Medical Association · 2025Article
- Article
97 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPostlicensure data has identified a causal link between rotavirus vaccines and intussusception in some settings. As rotavirus vaccines are introduced globally, monitoring intussusception will be crucial for ensuring safety of the vaccine programs.
methodsTo obtain updated information on background rates and clinical management of intussusception, we reviewed studies of intussusception in children <18 years of age published since 2002. We assessed the incidence of intussusception by month of life among children <1 year of age, seasonality, method of diagnosis, treatment, and case-fatality.
findingsWe identified 82 studies from North America, Asia, Europe, Oceania, Africa, Eastern Mediterranean, and Central & South America that reported a total of 44,454 intussusception events. The mean incidence of intussusception was 74 per 100,000 (range: 9-328) among children <1 year of age, with peak incidence among infants 5-7 months of age. No seasonal patterns were observed. A radiographic modality was used to diagnose intussusception in over 95% of the cases in all regions except Africa where clinical findings or surgery were used in 65% of the cases. Surgical rates were substantially higher in Africa (77%) and Central and South America (86%) compared to other regions (13-29%). Case-fatality also was higher in Africa (9%) compared to other regions (<1%). The primary limitation of this review relates to the heterogeneity in intussusception surveillance across different regions.
conclusionThis review of the intussusception literature from the past decade provides pertinent information that should facilitate implementation of intussusception surveillance for monitoring the postlicensure safety of rotavirus vaccines.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.