ArticlePloS one2013
Proteogenomic analysis of a thermophilic bacterial consortium adapted to deconstruct switchgrass.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed, 71 citations in OpenAlex.
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- Teredinibacter turnerae secretome highlights key enzymes for plant cell wall degradation.Bioresources and bioprocessing · 2025Article
- Low-abundance populations distinguish microbiome performance in plant cell wall deconstruction.Microbiome · 2022Article
- Effects ofGenes · 2022Article
- Metaproteomics reveals enzymatic strategies deployed by anaerobic microbiomes to maintain lignocellulose deconstruction at high solids.Nature communications · 2022Article
- Thermophiles and carbohydrate-active enzymes (CAZymes) in biofilm microbial consortia that decompose lignocellulosic plant litters at high temperatures.Scientific reports · 2022Article
- Harnessing microbial wealth for lignocellulose biomass valorization through secretomics: a review.Biotechnology for biofuels · 2021Review
- Deconstruction of Lignin: From Enzymes to Microorganisms.Molecules (Basel, Switzerland) · 2021Review
- Cellulase-Hemicellulase Activities and Bacterial Community Composition of Different Soils from Algerian Ecosystems.Microbial ecology · 2019Article
- Conservation of Endophyte Bacterial Community Structure Across TwoFrontiers in microbiology · 2019Article
- Engineering glycoside hydrolase stability by the introduction of zinc binding.Acta crystallographica. Section D, Structural biology · 2018Article
- A bacterial pioneer produces cellulase complexes that persist through community succession.Nature microbiology · 2018Article
- Temporal Expression Dynamics of Plant Biomass-Degrading Enzymes by a Synthetic Bacterial Consortium Growing on Sugarcane Bagasse.Frontiers in microbiology · 2018Article
- Bacterial laccase: recent update on production, properties and industrial applications.3 Biotech · 2017Review
- 1,003 reference genomes of bacterial and archaeal isolates expand coverage of the tree of life.Nature biotechnology · 2017Article
- Revealing the insoluble metasecretome of lignocellulose-degrading microbial communities.Scientific reports · 2017Article
- Expression of naturally ionic liquid-tolerant thermophilic cellulases in Aspergillus niger.PloS one · 2017Article
- Diversity of microbial carbohydrate-active enzymes in Danish anaerobic digesters fed with wastewater treatment sludge.Biotechnology for biofuels · 2017Article
- Genome-Centric Analysis of a Thermophilic and Cellulolytic Bacterial Consortium Derived from Composting.Frontiers in microbiology · 2017Article
- Microbial community structure and dynamics in thermophilic composting viewed through metagenomics and metatranscriptomics.Scientific reports · 2016Article
Corrections and comments
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Authors and funding
13 authors at 7 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Thermophilic bacteria are a potential source of enzymes for the deconstruction of lignocellulosic biomass. However, the complement of proteins used to deconstruct biomass and the specific roles of different microbial groups in thermophilic biomass deconstruction are not well-explored. Here we report on the metagenomic and proteogenomic analyses of a compost-derived bacterial consortium adapted to switchgrass at elevated temperature with high levels of glycoside hydrolase activities. Near-complete genomes were reconstructed for the most abundant populations, which included composite genomes for populations closely related to sequenced strains of Thermus thermophilus and Rhodothermus marinus, and for novel populations that are related to thermophilic Paenibacilli and an uncultivated subdivision of the little-studied Gemmatimonadetes phylum. Partial genomes were also reconstructed for a number of lower abundance thermophilic Chloroflexi populations. Identification of genes for lignocellulose processing and metabolic reconstructions suggested Rhodothermus, Paenibacillus and Gemmatimonadetes as key groups for deconstructing biomass, and Thermus as a group that may primarily metabolize low molecular weight compounds. Mass spectrometry-based proteomic analysis of the consortium was used to identify >3000 proteins in fractionated samples from the cultures, and confirmed the importance of Paenibacillus and Gemmatimonadetes to biomass deconstruction. These studies also indicate that there are unexplored proteins with important roles in bacterial lignocellulose deconstruction.
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