ArticleTopics in stroke rehabilitation
High-versus low-frequency stimulation effects on fine motor control in chronic hemiplegia: a pilot study.
Article in Topics in stroke rehabilitation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Impact of Direct Current Neuromuscular Electrical Stimulation on Physical Therapy Treatment of Peripheral Neuropathy
Impact of Direct Current Neuromuscular Electrical Stimulation on Physical Therapy Treatment of Lumbosacral Radiculopathy
Who cites it
13 citing papers in PubMed, 27 citations in OpenAlex.
- An Open-Label Comparative Study of the Impact of Two Types of Electrical Stimulation (Direct Current Neuromuscular Electrical Stimulation and Transcutaneous Electrical Stimulation) on Physical Therapy Treatment of Diabetic Peripheral Neuropathy.Journal of diabetes research · 2025Trial
- A randomised clinical trial comparing 35 Hz versus 50 Hz frequency stimulation effects on hand motor recovery in older adults after stroke.Scientific reports · 2021Trial
- Prediction of swallowing improvement after tracheal reconstruction in patients receiving LFES-containing rehabilitation: a retrospective cohort study.Frontiers in surgery · 2026Article
- Acute changes in ankle dorsiflexor strength and fNIRS-Derived cortical activation following a single session of neuromuscular electrical stimulation in healthy older adults.Frontiers in aging · 2026Article
- Exploratory Evaluation for Functional Changes of Six-Month Systematic Non-Invasive Electrical Stimulation in a Whole-Body Suit on Children with Cerebral Palsy GMFCS III-V.Neurology international · 2025Article
- Case Study: The Benefits of the Neubie Direct Current Electrical Stimulation Device for Pain, Spasticity, and Movement in Amyotrophic Lateral Sclerosis.Integrative medicine (Encinitas, Calif.) · 2025Article
- Effect of Neuromuscular Electrical Stimulation Training on Control of Involuntary Muscular Torque and Stimulation Intensity in Older Adults.International journal of exercise science · 2023Article
- Skeletal muscle stiffness as measured by magnetic resonance elastography after chronic spinal cord injury: a cross-sectional pilot study.Neural regeneration research · 2021Article
- Reporting for Duty: The duty cycle in Functional Electrical Stimulation research. Part I: Critical commentaries of the literature.European journal of translational myology · 2018Article
- Effects of Neuromuscular Electrical Stimulation Training on Endurance Performance.Frontiers in physiology · 2016Article
- Efficacy of functional electrical stimulation at different frequencies for post-stroke foot drop: a retrospective cohort study.Frontiers in neurologyArticle
- The use of functional electrical stimulation to improve upper limb function in children with hemiplegic cerebral palsy: A feasibility study.Journal of rehabilitation and assistive technologies engineeringArticle
- Neuromuscular Electrical Stimulation for Treatment of Muscle Impairment: Critical Review and Recommendations for Clinical Practice.Physiotherapy Canada. Physiotherapie CanadaArticle
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundThe optimal parameters of neuromuscular electrical stimulation (NMES) for recovery of hand function after stroke are not known. This clinical pilot study examined whether higher or lower frequencies are more effective for improving fine motor control of the hand in a chronic poststroke population.
methodsA 1-month, 4 times per week, in-home regimen of either a high-frequency (40 Hz) or low-frequency (20 Hz) NMES program was applied to the hemiplegic thenar muscles of 16 persons with chronic stroke. Participants were identified a priori as having a low level of function (LF) or a high level of function (HF). Outcome measures of strength, dexterity, and endurance were measured before and after participation in the regimen.
resultsLF subjects showed no significant changes with either the high- or the low-frequency NMES regimen. HF subjects showed significant changes in strength, dexterity, and endurance. Within this group, higher frequencies of stimulation yielded strength gains and increased motor activation; lower frequencies affected dexterity and endurance.
conclusionsThe results suggest that higher frequencies of stimulation could be more effective in improving strength and motor activation properties and that lower frequencies may affect coordination and endurance changes. Results also indicate that persons with a higher functional level of recovery may respond more favorably to NMES regimens, but further study with larger patient groups is warranted.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.