Evidence map›Paper›PMID 23892827›Full record

ArticleNicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco2014

Thirdhand tobacco smoke: a tobacco-specific lung carcinogen on surfaces in smokers' homes.

Janet L Thomas, Stephen S Hecht, Xianghua Luo, Xun Ming, Jasjit S Ahluwalia, Steven G Carmella

Abstract read
In one paragraph

Article in Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.

  1. Analysis of Assessment Methods for Detecting Nicotine Residue and Its Impact on Humans: A Systematic Review.International journal of environmental research and public health · 2025
    Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Thirdhand Smoke May Promote Lung Adenocarcinoma Development through HN1.Computational and mathematical methods in medicine · 2023
    Article
  7. Article
  8. Thirdhand smoke: Genotoxicity and carcinogenic potential.Chronic diseases and translational medicine · 2020
    Article
  9. Review
  10. Article
  11. Article
  12. The American journal of tropical medicine and hygiene · 2017
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Children's exposure to secondhand and thirdhand smoke carcinogens and toxicants in homes of hookah smokers.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2014
    Article
  18. Thirdhand Smoke: State of the Science and a Call for Policy Expansion.Public health reports (Washington, D.C. : 1974)
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Janet L ThomasMasonic Cancer Center, University of Minnesota, Minneapolis, MN.
Stephen S Hecht
Xianghua Luo
Xun Ming
Jasjit S Ahluwalia
Steven G Carmella
University of Minnesota · US

Funding

Women's CancerP30CA077598 · NCI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI HEATHER Hammond NELSON · 1998 to 2026
$100.4M
University of Minnesota Clinical and Translational Science Institute (UMN CTSI)UL1TR000114 · NCATS · UNIVERSITY OF MINNESOTA · PI BLAZAR, BRUCE R · 2012 to 2015
$35.0M
METABOLISM OF CARCINOGENIC TOBACCO SPECIFIC NITROSAMINESR01CA081301 · NCI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI STEPHEN S HECHT · 1999 to 2026
$7.1M
The Center for Health Disparities Research, Engagement, and Training (CeHDRET)P60MD003422 · NIMHD · UNIVERSITY OF MINNESOTA · PI EVERSON-ROSE, SUSAN A. · 2009 to 2013
$6.1M
Metabolism of Carcinogenic Tobacco-Specific NitrosaminesR37CA081301 · NCI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI HECHT, STEPHEN S · 2004 to 2013
$5.5M
NCATS NIH HHS UL1 TR000114NCI NIH HHS CA-81301NCI NIH HHS P30 CA077598NCI NIH HHS R01 CA081301NIMHD NIH HHS P60MD003422
6 · The paper itself

Abstract

introductionThirdhand tobacco smoke consists of substances remaining on the surfaces or in the dust of areas where people have smoked. While previous studies have demonstrated the presence of nicotine and various other constituents of tobacco smoke on surfaces in smokers' homes, none has investigated the presence of tobacco-specific carcinogens.

methodsWe used liquid chromatography-tandem mass spectrometry to analyze surface dust samples from both the homes of smokers and nonsmokers for the powerful tobacco-specific lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).

resultsWe positively identified NNK on surfaces in 33 of 37 smokers' homes (700±788 pg/100cm(2) [range, not detected-3,500 pg/100cm(2)]), but only in 3 of 19 nonsmokers' homes (235±176 pg/100cm(2) in the homes where NNK was detected [range, not detected-435 pg/100cm(2)]). The differences in occurrence and levels of NNK in the homes of smokers and nonsmokers were significant (p < .0001).

conclusionsThe powerful tobacco-specific lung carcinogen NNK is present on surfaces in most homes occupied by smokers. Potential renters or buyers of apartments or homes should be notified if previous residents were smokers in order to avoid unnecessary exposure of their families to a potent lung carcinogen.

Indexed as

AdultCarcinogensChildChromatography, LiquidFemaleHumansLung NeoplasmsMaleNitrosaminesSmokingTandem Mass SpectrometryTobacco Smoke Pollution4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanoneCarcinogensNitrosaminesTobacco Smoke Pollution

Identifiers

PMID23892827
PMCPMC3864489
OpenAlexW2133457805

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.