Evidence map›Paper›PMID 23892775›Full record

ArticleChronic illness2014

Characteristics of diabetic patients associated with achieving and maintaining blood pressure targets in the Adherence and Intensification of Medications program.

Mandi L Klamerus, Eve A Kerr, Hayden B Bosworth, Julie A Schmittdiel, Michele Heisler

Registry-linked trialAbstract readEvaluation Study
In one paragraph

Article in Chronic illness, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00495794 (Adherence and Intensification of Medications), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00495794 nacompletednot on this map

Adherence and Intensification of Medications: A Population-Based Clinical Pharmacists Implementation Study Among Hypertensive Diabetes Patients

TypeinterventionalSponsorUS Department of Veterans AffairsRan2008 to 2012Enrolled4,622ConditionsDiabetes, HypertensionArmsClinical pharmacist-based intervention
3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Yonder: Grandparenthood, rural health, diabetes, & perinatal psychiatry.The British journal of general practice : the journal of the Royal College of General Practitioners · 2014
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mandi L Klamerus1Center for Clinical Management Research, Veterans Affairs (VA) Ann Arbor Healthcare System, Ann Arbor, MI.
Eve A Kerr
Hayden B Bosworth
Julie A Schmittdiel
Michele Heisler

Funding

Research BaseP30DK092926 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MARY ELLEN MICHELE HEISLER, ADESUWA B OLOMU · 2011 to 2026
$10.0M
Translational Research Core - Health Engagement & Action Translational (HEAT)P30DK092924 · NIDDK · KAISER FOUNDATION RESEARCH INSTITUTE · PI Alyce Sophia Adams, HILARY Kessler SELIGMAN · 2011 to 2026
$9.2M
Improving Adherence and Intensification of Medications Among Diabetes PatientsR18DK076622 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KERR, EVE A · 2007 to 2010
$2.1M
NIDDK NIH HHS 1P30-DK092924NIDDK NIH HHS 5 R18 DK076622NIDDK NIH HHS P30 DK092924NIDDK NIH HHS P30 DK092926NIDDK NIH HHS P30DK092926NIDDK NIH HHS R18 DK076622
6 · The paper itself

Abstract

objectivesTo determine patient characteristics associated with achieving and sustaining blood pressure (BP) targets in the Adherence and Intensification of Medications program, a program led by pharmacists trained in motivational interviewing and authorized to make BP medication changes.

methodsWe conducted a retrospective cohort study of patients with diabetes and persistent hypertension in Kaiser Permanente and the Department of Veterans Affairs. Using two-level logistic regression, baseline survey data from 458 program participants were examined to determine patient characteristics associated with (1) discharge from the program with a target BP (short-term success) and (2) maintenance of the target BP over a nine-month period (long-term success).

resultsIn multivariable analyses, patients who screened positive for depression or had a higher baseline systolic BP were less likely to achieve short-term success (adjusted odds ratio (AOR) 0.42 [95% confidence interval (CI): 0.19-0.93], p = 0.03; AOR 0.94 [0.91-0.97], p < 0.01; respectively). Patients who reported at baseline one or more barriers to medication adherence were less likely to achieve long-term success (AOR 0.50 [0.26-0.94], p = 0.03).

conclusionsAlthough almost 90% of patients achieved short-term success, only 28% achieved long-term success. Baseline barriers to adherence were associated with lack of long-term success and could be the target of maintenance programs for patients who achieve short-term success.

Indexed as

Medication AdherenceAgedAntihypertensive AgentsDiabetes ComplicationsFemaleFollow-Up StudiesHumansHypertensionLogistic ModelsMaleMiddle AgedMultivariate AnalysisRetrospective StudiesSelf EfficacySocial SupportSocioeconomic FactorsAntihypertensive AgentsBlood pressurediabetesmedication adherencequestionnaires

Identifiers

PMID23892775
PMCPMC4134130

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.