Evidence map›Paper›PMID 23892447›Full record

ReviewVascular medicine (London, England)2013

Endothelial microparticles: sophisticated vesicles modulating vascular function.

Anne M Curtis, Jay Edelberg, Rebecca Jonas, Wade T Rogers, Jonni S Moore, Wajihuddin Syed, Emile R Mohler

Open access · greenAbstract readReview
In one paragraph

Review in Vascular medicine (London, England), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 1 synthesis or guideline pooled it, 96 citations in OpenAlex.

  1. Pooled it
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  5. Review
  6. Extracellular vesicles related to familial hypercholesterolemia.Archives of endocrinology and metabolism · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Anne M CurtisTrinity Biomedical Science Institute (TBSI), Dublin, Ireland. acurtis@tcd.ie
Jay Edelberg
Rebecca Jonas
Wade T Rogers
Jonni S Moore
Wajihuddin Syed
Emile R Mohler
University of Pennsylvania · USSanofi (United States) · USTrinity College Dublin · IE

Funding

Validation of a Vascular Health Profile for Cardiovascular DiseaseRC1HL099528 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI MOHLER, EMILE R. · 2009 to 2010
$933k
NHLBI NIH HHS RC1 HL099528
6 · The paper itself

Abstract

Endothelial microparticles (EMPs) belong to a family of extracellular vesicles that are dynamic, mobile, biological effectors capable of mediating vascular physiology and function. The release of EMPs can impart autocrine and paracrine effects on target cells through surface interaction, cellular fusion, and, possibly, the delivery of intra-vesicular cargo. A greater understanding of the formation, composition, and function of EMPs will broaden our understanding of endothelial communication and may expose new pathways amenable for therapeutic manipulation.

Indexed as

Cell CommunicationSignal TransductionAnimalsCell-Derived MicroparticlesEndothelial CellsEndothelium, VascularHumansVascular Diseasesendothelial dysfunctionendothelial microparticlestherapeuticsvesiculation

Identifiers

PMID23892447
PMCPMC4437568
OpenAlexW2111686577

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.