Evidence map›Paper›PMID 23892225›Full record

ArticleEnvironment international2013

Associations between socioeconomic status and environmental toxicant concentrations in adults in the USA: NHANES 2001-2010.

Jessica Tyrrell, David Melzer, William Henley, Tamara S Galloway, Nicholas J Osborne

Open access · hybridAbstract read
PubMed Publisher
In one paragraph

Article in Environment international, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 105 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
105citing papers in PubMed, 2 pooled it
8.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

105 citing papers in PubMed, 2 syntheses or guidelines pooled it, 221 citations in OpenAlex.

  1. Pooled it
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  9. Relevance and challenges of exposome studies for environmental health research.Environmental health : a global access science source · 2026
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45 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jessica TyrrellEuropean Centre for Environment and Human Health, University of Exeter Medical School, University of Exeter, United Kingdom.
David Melzer
William Henley
Tamara S Galloway
Nicholas J Osborne
University of Exeter · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Low level chronic exposure to toxicants is associated with a range of adverse health effects. Understanding the various factors that influence the chemical burden of an individual is of critical importance to public health strategies. We investigated the relationships between socioeconomic status (SES) and bio-monitored chemical concentration in five cross-sectional waves of the U.S. National Health and Nutrition Examination Survey (NHANES). We utilised adjusted linear regression models to investigate the association between 179 toxicants and the poverty income ratio (PIR) for five NHANES waves. We then selected a subset of chemicals associated with PIR in 3 or more NHANES waves and investigated potential mediating factors using structural equation modelling. PIR was associated with 18 chemicals in 3 or more NHANES waves. Higher SES individuals had higher burdens of serum and urinary mercury, arsenic, caesium, thallium, perfluorooctanoic acid, perfluorononanoic acid, mono(carboxyoctyl) phthalate and benzophenone-3. Inverse associations were noted between PIR and serum and urinary lead and cadmium, antimony, bisphenol A and three phthalates (mono-benzyl, mono-isobutyl, mono-n-butyl). Key mediators included fish and shellfish consumption for the PIR, mercury, arsenic, thallium and perfluorononanoic acid associations. Sunscreen use was an important mediator in the benzophenone-3/PIR relationship. The association between PIR and cadmium or lead was partially mediated by smoking, occupation and diet. These results provide a comprehensive analysis of exposure patterns as a function of socioeconomic status in US adults, providing important information to guide future public health remediation measures to decrease toxicant and disease burdens within society.

Indexed as

Environmental ExposureSocial ClassAdolescentAdultAgedAnimalsBenzhydryl CompoundsBenzophenonesBisphenol A CompoundsCadmiumCaprylatesCross-Sectional StudiesDietEnvironmental MonitoringEnvironmental PollutantsFemaleBenzhydryl CompoundsBenzophenonesbisphenol ABisphenol A CompoundsCadmiumCaprylatesEnvironmental PollutantsFluorocarbonsMercuryoxybenzoneperfluorooctanoic acidPhenolsphthalic acidPhthalic AcidsChemical toxicantsEnvironmentNational Health and Nutrition Examination SurveyNHANESPIRPoverty Income RatioSESSocio-economic statusSocioeconomic status

Identifiers

PMID23892225
OpenAlexW1995934935

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.