ReviewRespiratory physiology & neurobiology2013
Respiration following spinal cord injury: evidence for human neuroplasticity.
Review in Respiratory physiology & neurobiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 42 citations in OpenAlex.
- Diverse Transcriptional Alterations in V2a Propriospinal Neurons Following Spinal Cord Injury.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- V2a neurons restore diaphragm function in mice following spinal cord injury.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Respiratory plasticity following spinal cord injury: perspectives from mouse to man.Neural regeneration research · 2022Review
- Effect of vocal respiratory training on respiratory function and respiratory neural plasticity in patients with cervical spinal cord injury: a randomized controlled trial.Neural regeneration research · 2022Article
- Effect of Vocal Exercise on Respiratory Function and Voice Quality in Patients with Cervical Spinal Cord Injury: A Mini-review.Progress in rehabilitation medicine · 2022Review
- Risk Factors for Tracheostomy after Traumatic Cervical Spinal Cord Injury: A 10-Year Study of 456 Patients.Orthopaedic surgery · 2022Article
- Effectiveness of oral motor respiratory exercise and vocal intonation therapy on respiratory function and vocal quality in patients with spinal cord injury: a randomized controlled trial.Neural regeneration research · 2021Article
- Respiratory Training and Plasticity After Cervical Spinal Cord Injury.Frontiers in cellular neuroscience · 2021Review
- Development and validation of models to predict respiratory function in persons with long-term spinal cord injury.Spinal cord · 2019Article
- Diaphragm ultrasonography and pulmonary function tests in patients with spinal cord injury.Spinal cord · 2019Article
- The Neuroplastic and Therapeutic Potential of Spinal Interneurons in the Injured Spinal Cord.Trends in neurosciences · 2018Review
- Integration of Transplanted Neural Precursors with the Injured Cervical Spinal Cord.Journal of neurotrauma · 2018Article
- Spontaneous respiratory plasticity following unilateral high cervical spinal cord injury in behaving rats.Experimental neurology · 2018Article
- Anatomical Recruitment of Spinal V2a Interneurons into Phrenic Motor Circuitry after High Cervical Spinal Cord Injury.Journal of neurotrauma · 2017Article
- Improving the therapeutic efficacy of neural progenitor cell transplantation following spinal cord injury.Expert review of neurotherapeutics · 2017Review
- Plasticity in respiratory motor neurons in response to reduced synaptic inputs: A form of homeostatic plasticity in respiratory control?Experimental neurology · 2017Review
- Enhancing neural activity to drive respiratory plasticity following cervical spinal cord injury.Experimental neurology · 2017Review
- Neuroprotective and Neurorestorative Processes after Spinal Cord Injury: The Case of the Bulbospinal Respiratory Neurons.Neural plasticity · 2016Review
- Hypoxia triggers short term potentiation of phrenic motoneuron discharge after chronic cervical spinal cord injury.Experimental neurology · 2015Article
- Cortical reorganization after spinal cord injury: always for good?Neuroscience · 2014Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Respiratory dysfunction is one of the most devastating consequences of cervical spinal cord injury (SCI) with impaired breathing being a leading cause of morbidity and mortality in this population. However, there is mounting experimental and clinical evidence for moderate spontaneous respiratory recovery, or "plasticity", after some spinal cord injuries. Pre-clinical models of respiratory dysfunction following SCI have demonstrated plasticity at neural and behavioral levels that result in progressive recovery of function. Temporal changes in respiration after human SCI have revealed some functional improvements suggesting plasticity paralleling that seen in experimental models-a concept that has been previously under-appreciated. While the extent of spontaneous recovery remains limited, it is possible that enhancing or facilitating neuroplastic mechanisms may have significant therapeutic potential. The next generation of treatment strategies for SCI and related respiratory dysfunction should aim to optimize these recovery processes of the injured spinal cord for lasting functional restoration.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.