Evidence map›Paper›PMID 23891559›Full record

ReviewLife sciences2014

"Herbal incense": designer drug blends as cannabimimetics and their assessment by drug discrimination and other in vivo bioassays.

Torbjörn U C Järbe, Roger S Gifford

Open access · greenAbstract readComparative StudyReview
In one paragraph

Review in Life sciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
4.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
  2. Review
  3. Molecular Mechanism and Cannabinoid Pharmacology.Handbook of experimental pharmacology · 2020
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. The Changing Face of Recreational Drug Use.Cerebrum : the Dana forum on brain science
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Torbjörn U C JärbeCenter for Drug Discovery, Department of Pharmaceutical Sciences, Northeastern University, Boston, MA 02115, USA. Electronic address: t.jarbe@neu.edu.
Roger S GiffordCenter for Drug Discovery, Department of Pharmaceutical Sciences, Northeastern University, Boston, MA 02115, USA.
Northeastern University · US

Funding

Exogenous/endogenous cannabinoids--A comparisonR01DA009064 · NIDA · TEMPLE UNIVERSITY · PI MAKRIYANNIS, ALEXANDROS · 1995 to 2016
$3.2M
NIDA NIH HHS 5R01DA 009064-19NIDA NIH HHS R01 DA009064
6 · The paper itself

Abstract

Recently, synthetic cannabinoids originally designed for testing in the laboratory only have found use recreationally in designer herbal blends, originally called "Spice". The myriad of compounds found are for the most part potent full agonists of the cannabinoid receptor 1, producing effects similar to tetrahydrocannabinol (THC) and marijuana. Drug discrimination of these compounds offers a specific behavioral test that can help determine whether these new synthetic compounds share a similar "subjective high" with the effects of marijuana/THC. By utilization of drug discrimination and other behavioral techniques, a better understanding of these new "designer" cannabinoids may be reached to assist in treating both the acute and chronic effects of these drugs. The paper provides a brief exposé of modern cannabinoid research as a backdrop to the recreational use of designer herbal blend cannabimimetics.

Indexed as

AnimalsBiological AssayCannabinoid Receptor AgonistsCannabinoidsCannabisDesigner DrugsDronabinolHumansReceptor, Cannabinoid, CB1Cannabinoid Receptor AgonistsCannabinoidsDesigner DrugsDronabinolReceptor, Cannabinoid, CB1BioassaysDrug discriminationSynthetic marijuanaTHC

Identifiers

PMID23891559
PMCPMC4135441
OpenAlexW2066195767

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.