Evidence map›Paper›PMID 23891035›Full record

SynthesisDrug and alcohol dependence2013

Gender disparities in HIV infection among persons who inject drugs in Central Asia: a systematic review and meta-analysis.

Don C Des Jarlais, Azizbek Boltaev, Jonathan Feelemyer, Heidi Bramson, Kamyar Arasteh, Benjamin W Phillips, Holly Hagan

Open access · greenAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Drug and alcohol dependence, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Trial
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Don C Des JarlaisThe Baron Edmond de Rothschild Chemical Dependency Institute, Beth Israel Medical Center, New York City, USA. Electronic address: ddesjarlais@chpnet.org.
Azizbek Boltaev
Jonathan Feelemyer
Heidi Bramson
Kamyar Arasteh
Benjamin W Phillips
Holly Hagan
Mount Sinai Beth Israel · USAIDS United · USNew York University · US

Funding

Multiple HIV Prevention Packages for IDUs in EstoniaR01AI083035 · NIAID · BETH ISRAEL MEDICAL CTR (NEW YORK) · PI DES JARLAIS, DON C · 2009 to 2012
$2.5M
NIAID NIH HHS R01 AI083035NIAID NIH HHS R01 AI083035-05
6 · The paper itself

Abstract

objectiveDisparities in HIV infection, with females having higher rates of HIV infection than males, have been noted among persons who inject drugs (PWID) in many countries. We examined male/female HIV disparities among PWID in Central Asia and compared these disparities with patterns worldwide.

methodsA systematic review and meta-analyses were conducted for studies reporting HIV prevalence by gender among PWID. To be included in the analyses, reports had to contain (1) samples of PWID from Central Asia, (2) HIV data based on laboratory testing, (3) HIV prevalence reported for males and females, and (4) samples that were not recruited on the basis of HIV status.

resultsData were abstracted from 11 studies in 5 countries in Central Asia: China, Kazakhstan, Russia, Tajikistan, and Uzbekistan; the total sample size was 12,225. The mean weighted OR for HIV prevalence among females to males was 0.913 (95% CI 0.07, 1.26), with high heterogeneity among studies (I(2)=70.0%) and a possible publication bias among studies with small sample sizes (Eggers test=-1.81, 95% CI -5.18, 0.54).

conclusionsThe non-significant higher HIV prevalence among male PWID in Central Asia contrasts with the worldwide findings which show slightly higher HIV prevalence among female PWID. This may reflect the relative recency of the HIV epidemics in Central Asia. The findings also suggest there may be factors that protect female PWID from HIV in some settings. Further examination of transmission dynamics in Central Asia is necessary to better understand the HIV epidemic among PWID.

Indexed as

Sex CharacteristicsAsiaDrug UsersFemaleHIV InfectionsHIV SeropositivityHumansMalePrevalenceRisk FactorsSubstance Abuse, IntravenousCentral AsiaGenderHIVPeople who inject drugs (PWID)Prevalence

Identifiers

PMID23891035
PMCPMC3825744
OpenAlexW2090006211

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.