ReviewThe Veterinary clinics of North America. Small animal practice2013
Feline drug metabolism and disposition: pharmacokinetic evidence for species differences and molecular mechanisms.
Review in The Veterinary clinics of North America. Small animal practice, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
70 citing papers in PubMed, 139 citations in OpenAlex.
- Bioavailability of paracetamol with/without caffeine in Egyptian patients with hepatitis C virus.European journal of clinical pharmacology · 2016Trial
- Antiepileptic drug therapy in companion animals: New perspectives on clinical pathology monitoring.Veterinary and animal science · 2026Review
- Review
- Network Pharmacology and Molecular Simulation Reveal Potential Targets and Pathways of Vine Tea in Feline Intestinal Inflammation.Veterinary sciences · 2026Article
- Formulation and In Vitro Evaluation of Red Palm Oil withVeterinary sciences · 2026Article
- The Pharmacokinetics of Intravenous and Subcutaneous Ondansetron in Female Beagle Dogs.Journal of veterinary pharmacology and therapeutics · 2026Article
- In vitro immunotoxicity of important mycotoxins detected in commercial dry dog and cat food in relation to internal exposure.Mycotoxin research · 2026Article
- Development and Validation of LC-MS/MS Methods for Quantification of Fluralaner and Moxidectin in Cat Plasma and Its Application in a Pharmacokinetic Study.Animals : an open access journal from MDPI · 2026Article
- Omeprazole as a Novel Treatment Option for Giardiasis in Cats.Veterinary medicine and science · 2026Article
- Effect of Intravenous Lipid Emulsion Therapy on Xenobiotic Plasma Partitioning and Short-Term Neurological Outcome in Companion Animals with Suspected Neurotoxicosis: A Case Series.Animals : an open access journal from MDPI · 2026Article
- Biotransformation and detoxification enzyme (CYP1A2, CYP2E1, and GST) activities in vital organs of rats using liver extracts ofOpen veterinary journal · 2026Article
- Safety and efficacy of a feed additive consisting of a proanthocyanidin-rich dry extract from the fruit ofEFSA journal. European Food Safety Authority · 2026Article
- Alopecia management from a comparative perspective: pharmacological and pharmaceutical insights in humans, dogs, and cats.Frontiers in veterinary science · 2026Review
- One Health Approach to Sporothrix brasiliensis: Disinfection Strategies for Control and Prevention.Revista da Sociedade Brasileira de Medicina Tropical · 2026Article
- Efficacy of combined grapiprant and tapentadol for analgesia in cats undergoing elective ovariohysterectomy.Journal of feline medicine and surgery · 2026Article
- Systemic gene expression mapping of voltage-gated calcium channel α1-subunits in cats.Open veterinary journal · 2025Article
- Comparative Pharmacological and Pharmaceutical Perspectives on Antidiabetic Therapies in Humans, Dogs, and Cats.Pharmaceutics · 2025Review
- Exposure of Domestic Cats (Toxics · 2025Article
- Evaluation of Violacein Metabolic Stability and Metabolite Identification in Human, Mouse, and Rat Liver Microsomes.Pharmaceutics · 2025Article
- Anti-inflammatory drugs as potential antimicrobial agents: a review.Frontiers in pharmacology · 2025Review
10 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Although it is widely appreciated that cats respond differently to certain drugs compared with other companion animal species, the causes of these differences are poorly understood. This article evaluates published evidence for altered drug effects in cats, focusing on pharmacokinetic differences between cats, dogs, and humans, and the molecular mechanisms underlying these differences. More work is needed to better understand drug metabolism and disposition differences in cats, thereby enabling more rational prescribing of existing medications, and the development of safer drugs for this species.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.