ArticleGlobalization and health2013
Global health initiative investments and health systems strengthening: a content analysis of global fund investments.
Article in Globalization and health, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers, 4 of them syntheses that pooled it.
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Who cites it
64 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Evolution and effectiveness of bilateral and multilateral development assistance for health: a mixed-methods review of trends and strategic shifts (1990-2022).BMJ global health · 2025Pooled it
- Barriers against and strategies for malaria control during the COVID-19 pandemic in low- and middle-income countries: a systematic review.Malaria journal · 2023Pooled it
- Using routine health information data for research in low- and middle-income countries: a systematic review.BMC health services research · 2020Pooled it
- Improving social accountability processes in the health sector in sub-Saharan Africa: a systematic review.BMC public health · 2018Pooled it
- System-wide investments generate health and enhance HIV, TB and malaria control in Malawi.Nature communications · 2026Article
- Evidence based mental health interventions for children in fragile and conflict affected settings: expanding reach and system strengthening.BMJ (Clinical research ed.) · 2026Article
- Impact of The Challenge Initiative on Public-Sector Family Planning Service Provision in Pakistan: Evidence from a Difference-in-Differences Analysis.Open access journal of contraception · 2026Article
- Global Health Initiatives and Universal Health Coverage in Pakistan-Aligned for the Future?The International journal of health planning and management · 2026Article
- The successful scaling-up of antiretroviral therapy globally has many lessons for advancing universal health coverage: progress at risk.Globalization and health · 2025Article
- Article
- Analysis of Health Systems Strengthening investment activities by Global Health Initiatives.BMC global and public health · 2025Article
- Ideas matter: An analysis of the effects of framing on health system strengthening in Zimbabwe.Health research policy and systems · 2025Article
- "They tossed me up like a ball": informal settlement residents' experiences in accessing healthcare in Kampala, Uganda.BMC public health · 2025Article
- What slows the progress of health systems strengthening at subnational level? A political economy analysis of three districts in Uganda.PLOS global public health · 2025Article
- Design and implementation of a Primary Health Care (PHC) Toolbox for improving the impact of support from Global Development Partners.BMC global and public health · 2024Article
- Investigating the citing communities around three leading health-system frameworks.Health research policy and systems · 2024Article
- From understanding to action: a juncture-factor framework for advancing social responsiveness in health professions education.Frontiers in medicine · 2024Article
- Ambitions and realities: Are Global Fund investments designed to achieve resilient and sustainable systems for health? Findings from the Global Fund Prospective Country Evaluation.PLOS global public health · 2024Article
- Evaluation of the administrative, coordination and financing capacity of the sub-national malaria elimination programs in Nigeria: a case study of cross river state.Journal of public health in Africa · 2023Article
- Rethinking international financing for health to better respond to future pandemics.BMJ global health · 2023Review
4 more citing papers are in PubMed but not listed here.
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMillions of dollars are invested annually under the umbrella of national health systems strengthening. Global health initiatives provide funding for low- and middle-income countries through disease-oriented programmes while maintaining that the interventions simultaneously strengthen systems. However, it is as yet unclear which, and to what extent, system-level interventions are being funded by these initiatives, nor is it clear how much funding they allocate to disease-specific activities - through conventional 'vertical-programming' approach. Such funding can be channelled to one or more of the health system building blocks while targeting disease(s) or explicitly to system-wide activities.
methodsWe operationalized the World Health Organization health system framework of the six building blocks to conduct a detailed assessment of Global Fund health system investments. Our application of this framework framework provides a comprehensive quantification of system-level interventions. We applied this systematically to a random subset of 52 of the 139 grants funded in Round 8 of the Global Fund to Fight AIDS, Tuberculosis and Malaria (totalling approximately US$1 billion).
resultsAccording to the analysis, 37% (US$ 362 million) of the Global Fund Round 8 funding was allocated to health systems strengthening. Of that, 38% (US$ 139 million) was for generic system-level interventions, rather than disease-specific system support. Around 82% of health systems strengthening funding (US$ 296 million) was allocated to service delivery, human resources, and medicines & technology, and within each of these to two to three interventions. Governance, financing, and information building blocks received relatively low funding.
conclusionsThis study shows that a substantial portion of Global Fund's Round 8 funds was devoted to health systems strengthening. Dramatic skewing among the health system building blocks suggests opportunities for more balanced investments with regard to governance, financing, and information system related interventions. There is also a need for agreement, by researchers, recipients, and donors, on keystone interventions that have the greatest system-level impacts for the cost-effective use of funds. Effective health system strengthening depends on inter-agency collaboration and country commitment along with concerted partnership among all the stakeholders working in the health system.
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