Evidence map›Paper›PMID 23889039›Full record

Trial reportPsychophysiology2013

Effects of aerobic conditioning on cardiovascular sympathetic response to and recovery from challenge.

M Lindgren, C Alex, P A Shapiro, P S McKinley, E N Brondolo, M M Myers, C J Choi, S Lopez-Pintado, R P Sloan

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Psychophysiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

M LindgrenSahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
C AlexSahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
P A ShapiroDepartment of Psychiatry, Columbia University Medical Center, New York, New York, USA.
P S McKinleyDepartment of Psychiatry, Columbia University Medical Center, New York, New York, USA.
E N BrondoloSt. John's University, Jamaica, New York, USA.
M M MyersDepartment of Psychiatry, Columbia University Medical Center, New York, New York, USA.
C J ChoiNew York State Psychiatric Institute, New York, New York, USA.
S Lopez-PintadoMailman School of Public Health, Columbia University, New York, New York, USA.
R P SloanDepartment of Psychiatry, Columbia University Medical Center, New York, New York, USA.

Funding

ZOLEDRONIC ACID IN PROSTATE CANCERM01RR000645 · NCRR · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI COLTEN, HARVEY R · 1985 to 2006
$27.0M
HOSTILITY REDUCTION AND AUTONOMIC CONTROL OF THE HEARTR01HL063872 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SLOAN, RICHARD P · 2000 to 2004
$2.2M
PSYCHOPHYSIOLOGIC STRESS, EXERCISE AND AUTONOMIC CONTROLR01HL061287 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SLOAN, RICHARD P · 1998 to 2001
$468k
CARDIOVASCULAR AUTONOMIC CONTROL IN STRESS AND ANXIETYK02MH001491 · NIMH · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SLOAN, RICHARD P · 1998 to 2002
$324k
NCRR NIH HHS M01 RR000645NCRR NIH HHS M01-RR00645NHLBI NIH HHS R01 HL061287NHLBI NIH HHS R01 HL063872NIMH NIH HHS K02 MH001491
6 · The paper itself

Abstract

Exercise has widely documented cardioprotective effects, but the mechanisms behind these effects are still poorly understood. Here, we test the hypothesis that aerobic training lowers cardiovascular sympathetic responses to and speeds recovery from challenge. We conducted a randomized, controlled trial contrasting aerobic versus strength training on indices of cardiac (pre-ejection period, PEP) and vascular (low-frequency blood pressure variability, LF-BPV) sympathetic responses to and recovery from psychological and orthostatic challenge in 149 young, healthy, sedentary adults. Aerobic and strength training did not alter PEP or LF-BPV reactivity to or recovery from challenge. These findings, from a large randomized, controlled trial using an intent-to-treat design, show that moderate aerobic exercise training has no effect on PEP and LF-BPV reactivity to or recovery from psychological or orthostatic challenge. In healthy young adults, the cardioprotective effects of exercise training are unlikely to be mediated by changes in sympathetic activity.

Indexed as

AdultBlood PressureCardiography, ImpedanceCardiovascular SystemElectrocardiographyExerciseFemaleHeart RateHumansMalePhysical Conditioning, HumanResistance TrainingStress, PhysiologicalStress, PsychologicalSympathetic Nervous SystemAerobic trainingNormal subjectsSympathetic nervous system reactivity and recovery

Identifiers

PMID23889039
PMCPMC3815518

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.