Evidence map›Paper›PMID 23888204›Full record

ArticleOrthopedic reviews2013

Prosthesis infections after orthopedic joint replacement: the possible role of bacterial biofilms.

Zhijun Song, Lotte Borgwardt, Niels Høiby, Hong Wu, Torben Sandberg Sørensen, Arne Borgwardt

Open access · goldAbstract read
In one paragraph

Article in Orthopedic reviews, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed
6.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 164 citations in OpenAlex.

  1. Evaluating chronic bone and soft tissue infections with [European journal of nuclear medicine and molecular imaging · 2026
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  3. Observational
  4. Adhesion and Colonization Intensity ofJournal of functional biomaterials · 2025
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  8. Article
  9. Article
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  11. Review
  12. Article
  13. Review
  14. Hyaluronic acid-British anti-Lewisite as a safer chelation therapy for the treatment of arthroplasty-related metallosis.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  15. Article
  16. Prosthetic joint infection caused by an imipenem-resistant Mycobacterium senegalense.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2023
    Article
  17. Article
  18. Review
  19. Article
  20. Article

5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Zhijun Song
Lotte Borgwardt
Niels Høiby
Hong Wu
Torben Sandberg Sørensen
Arne Borgwardt
Frederiksberg Hospital · DKRigshospitalet · DKSingapore Centre for Environmental Life Sciences Engineering · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prosthesis-related infection is a serious complication for patients after orthopedic joint replacement, which is currently difficult to treat with antibiotic therapy. Consequently, in most cases, removal of the infected prosthesis is the only solution to cure the infection. It is, therefore, important to understand the comprehensive interaction between the microbiological situation and the host immune responses that lead to prosthesis infections. Evidence indicates that prosthesis infections are actually biofilm-correlated infections that are highly resistant to antibiotic treatment and the host immune responses. The authors reviewed the related literature in the context of their clinical experience, and discussed the possible etiology and mechanism leading to the infections, especially problems related to bacterial biofilm, and prophylaxis and treatment of infection, including both microbiological and surgical measures. Recent progress in research into bacterial biofilm and possible future treatment options of prosthesis-related infections are discussed.

Indexed as

biofilmsdiagnosisprevention and controlprosthesis-related infections

Identifiers

PMID23888204
PMCPMC3718238
OpenAlexW1988978476

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.