An analysis of a 'community-driven' reconstruction of the human metabolic network.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

18 citing papers in PubMed, 42 citations in OpenAlex.

1. Frontiers in systems biology · 2024
   Article
2. An Analysis of Mechanisms for Cellular Uptake of miRNAs to Enhance Drug Delivery and Efficacy in Cancer Chemoresistance.Non-coding RNA · 2021
   Review
3. Menstrual cycle rhythmicity: metabolic patterns in healthy women.Scientific reports · 2018
   Article
4. Enhancing Drug Efficacy and Therapeutic Index through Cheminformatics-Based Selection of Small Molecule Binary Weapons That Improve Transporter-Mediated Targeting: A Cytotoxicity System Based on Gemcitabine.Frontiers in pharmacology · 2017
   Article
5. Analysis of drug-endogenous human metabolite similarities in terms of their maximum common substructures.Journal of cheminformatics · 2017
   Article
6. SYNBIOCHEM Synthetic Biology Research Centre, Manchester - A UK foundry for fine and speciality chemicals production.Synthetic and systems biotechnology · 2016
   Article
7. MetMaxStruct: A Tversky-Similarity-Based Strategy for Analysing the (Sub)Structural Similarities of Drugs and Endogenous Metabolites.Frontiers in pharmacology · 2016
   Article
8. A Dormant Microbial Component in the Development of Preeclampsia.Frontiers in medicine · 2016
   Review
9. libChEBI: an API for accessing the ChEBI database.Journal of cheminformatics · 2016
   Article
10. Event-based text mining for biology and functional genomics.Briefings in functional genomics · 2015
    Review
11. Synthetic biology for the directed evolution of protein biocatalysts: navigating sequence space intelligently.Chemical Society reviews · 2015
    Review
12. The apparent permeabilities of Caco-2 cells to marketed drugs: magnitude, and independence from both biophysical properties and endogenite similarities.PeerJ · 2015
    Article
13. Understanding the foundations of the structural similarities between marketed drugs and endogenous human metabolites.Frontiers in pharmacology · 2015
    Article
14. How drugs get into cells: tested and testable predictions to help discriminate between transporter-mediated uptake and lipoidal bilayer diffusion.Frontiers in pharmacology · 2014
    Review
15. Path2Models: large-scale generation of computational models from biochemical pathway maps.BMC systems biology · 2013
    Article
16. Recon 2.2: from reconstruction to model of human metabolism.Metabolomics : Official journal of the Metabolomic Society
    Article
17. A 'rule of 0.5' for the metabolite-likeness of approved pharmaceutical drugs.Metabolomics : Official journal of the Metabolomic Society
    Article
18. Molecular phenotyping of a UK population: defining the human serum metabolome.Metabolomics : Official journal of the Metabolomic Society
    Article

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

Authors and funding

3 authors at 1 institution in 1 country.

Funding

Abstract

Indexed as