Evidence map›Paper›PMID 23887885›Full record

ReviewMolecular & cellular proteomics : MCP2013

Proteolytic post-translational modification of proteins: proteomic tools and methodology.

Lindsay D Rogers, Christopher M Overall

Abstract readReview
In one paragraph

Review in Molecular & cellular proteomics : MCP, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

68 citing papers in PubMed.

  1. Overcoming Peptide Instability in Blood: Development and Validation of a Stabilized LC-MS/MS Method for a 15-mer Peptide B4-007 in Pharmacokinetic Studies.Microchemical journal : devoted to the application of microtechniques in all branches of science · 2026
    Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Citrullination in tumor immunity and therapy.The Journal of clinical investigation · 2025
    Review
  8. Article
  9. Review
  10. Review
  11. Review
  12. Review
  13. Review
  14. Mechanisms of assembly and remodelling of the extracellular matrix.Nature reviews. Molecular cell biology · 2024
    Review
  15. Review
  16. Review
  17. Article
  18. Review
  19. Origins, Technological Advancement, and Applications of Peptidomics.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
  20. Strategies and rules for tuning TCR-derived therapy.Expert reviews in molecular medicine · 2023
    Review

8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Lindsay D RogersDepartment of Biochemistry and Molecular Biology, Department of Oral Biological and Medical Sciences, and Centre for Blood Research, University of British Columbia, 4.401 Life Sciences Institute, 2350 Health Sciences Mall, Vancouver, British Columbia, V6T 1Z3, Canada.
Christopher M Overall

Funding

Canadian Institutes of Health Research
6 · The paper itself

Abstract

Proteolytic processing is a ubiquitous and irreversible post-translational modification involving limited and highly specific hydrolysis of peptide and isopeptide bonds of a protein by a protease. Cleavage generates shorter protein chains displaying neo-N and -C termini, often with new or modified biological activities. Within the past decade, degradomics and terminomics have emerged as significant proteomics subfields dedicated to characterizing proteolysis products as well as natural protein N and C termini. Here we provide an overview of contemporary proteomics-based methods, including specific quantitation, data analysis, and curation considerations, and highlight exciting new and emerging applications within these fields enabling in vivo analysis of proteolytic events.

Indexed as

Protein Processing, Post-TranslationalAmino Acid MotifsBiotinylationChromatography, LiquidCombinatorial Chemistry TechniquesHumansIsotope LabelingMass SpectrometryMolecular Sequence DataPeptide FragmentsProtein Structure, TertiaryProteolysisProteomeProteomicsSubstrate SpecificityPeptide FragmentsProteome

Identifiers

PMID23887885
PMCPMC3861706

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.