Evidence map›Paper›PMID 23887845›Full record

ArticleStroke2013

Adjunctive medical therapies for acute stroke thrombolysis: is there a CLEAR-ER choice?

Andrew D Barreto, Claudia Pedroza, James C Grotta

Registry-linked trialAbstract readEditorialComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Stroke, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00894803 (The "Combined Approach to Lysis Utilizing Eptifibatide and Rt-PA in Acute Ischemic Stroke-Enhanced Regimen"), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00894803 phase2completednot on this map

The "Combined Approach to Lysis Utilizing Eptifibatide and Rt-PA in Acute Ischemic Stroke-Enhanced Regimen" (CLEAR-ER Stroke Trial)

TypeinterventionalSponsorUniversity of CincinnatiRan2009 to 2012Enrolled126ConditionsIschemic Stroke, Stroke, Brain InfarctionArmsEptifibatide, rt-PA
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Andrew D Barreto
Claudia Pedroza
James C Grotta

Funding

U OF TEXAS HLTH SCI CTR HOUSTON CENTER FOR CLINICAL AND TRANSLATIONAL SCIENCESUL1RR024148 · NCRR · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MCPHERSON, DAVID D · 2006 to 2010
$27.9M
CTSA: K12 COMPONENTKL2RR024149 · NCRR · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MCPHERSON, DAVID D · 2006 to 2011
$6.7M
Center for Clinical and Translational SciencesTL1RR024147 · NCRR · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MCPHERSON, DAVID D · 2006 to 2011
$2.3M
NCRR NIH HHS KL2 RR024149NCRR NIH HHS TL1 RR024147NCRR NIH HHS UL1 RR024148
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Brain IschemiaEptifibatideFemaleFibrinolytic AgentsHumansIntracranial HemorrhagesMalePeptidesPlatelet Aggregation InhibitorsStrokeThrombolytic TherapyTissue Plasminogen ActivatorEptifibatideFibrinolytic AgentsPeptidesPlatelet Aggregation InhibitorsTissue Plasminogen ActivatorBayes theoremplatelet glycoprotein GPIIb-IIIa complexstrokethrombolytic therapy

Identifiers

PMID23887845
PMCPMC3845499

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.