ArticleAIDS (London, England)2013
Assessing the effect of HIV counselling and testing on HIV acquisition among South African youth.
Article in AIDS (London, England), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 4 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
29 citing papers in PubMed, 4 syntheses or guidelines pooled it, 48 citations in OpenAlex.
- Sexual behaviour change following HIV testing services: a systematic review and meta-analysis.Journal of the International AIDS Society · 2020Pooled it
- Recent levels and trends in HIV incidence rates among adolescent girls and young women in ten high-prevalence African countries: a systematic review and meta-analysis.The Lancet. Global health · 2019Pooled it
- The effect of HIV counselling and testing on HIV acquisition in sub-Saharan Africa: a systematic review.Sexually transmitted infections · 2016Pooled it
- Pooled it
- Characteristics of sexually experienced HIV testers aged 18 to 32 in rural South Africa: baseline results from a community-based trial, NIMH Project Accept (HPTN 043).BMC public health · 2014Trial
- Generalizing from qualitative data: a case example using critical realist thematic analysis and mechanism mapping to evaluate a community health worker-led screening program in India.Implementation science : IS · 2024Article
- Machine learning prediction of adolescent HIV testing services in Ethiopia.Frontiers in public health · 2024Article
- HIV/AIDS-related knowledge and attitudes towards HIV rapid testing among Chinese college students: Findings from a cross-sectional survey.Preventive medicine reports · 2023Article
- Assessing Condom Use and Views on HIV Counselling and Testing among TVET College Students in Limpopo Province, South Africa.International journal of environmental research and public health · 2023Article
- Article
- Factors Associated with HIV Testing among Reproductive Women Aged 15-49 Years in the Gambia: Analysis of the 2019-2020 Gambian Demographic and Health Survey.International journal of environmental research and public health · 2022Article
- Costs of implementing community-based intervention for HIV testing in sub-Saharan Africa: a systematic review.Implementation science communications · 2021Review
- Observational
- Factors affecting HIV counselling and testing among Ethiopian women aged 15-49.BMC infectious diseases · 2019Article
- Impact of HIV testing and treatment services on risky sexual behaviour in the uMgungundlovu District, KwaZulu-Natal, South Africa: a cross-sectional study.AIDS research and therapy · 2019Article
- National age-of-consent laws and adolescent HIV testing in sub-Saharan Africa: a propensity-score matched study.Bulletin of the World Health Organization · 2019Article
- Impact of Counseling Received by Adolescents Undergoing Voluntary Medical Male Circumcision on Knowledge and Sexual Intentions.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2018Article
- Sexual reproductive healthcare utilisation and HIV testing in an integrated adolescent youth centre clinic in Cape Town, South Africa.Southern African journal of HIV medicine · 2018Article
- Factors associated with acceptability of HIV self-testing (HIVST) among university students in a Peri-Urban area of the Democratic Republic of Congo (DRC).The Pan African medical journal · 2018Article
- The DREAMS core package of interventions: A comprehensive approach to preventing HIV among adolescent girls and young women.PloS one · 2018Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
Abstract
objectiveYouth aged 15-24 years in sub-Saharan Africa are at a high risk for HIV acquisition and urgently need HIV prevention interventions. HIV counselling and testing (HCT) is designed to promote HIV prevention. However the impact of HCT on HIV acquisition has never been assessed among youth. We assess the impact of HCT on HIV acquisition among South African youth.
designData came from an annual HIV survey for persons aged 15 years and over, nested within a socio-demographic household surveillance in a geographically defined area of KwaZulu-Natal. Within this population, we used data from 2006 to 2011 to construct a cohort of HIV-uninfected youth aged 15-24 years.
methodsWe compared youth who reported knowing their HIV status from HCT with those who reported not knowing their HIV status for time to HIV seroconversion using time-varying marginal structural Cox proportional hazards models.
resultsThe cohort included 3959 HIV-uninfected youth, of whom 1167 (29%) reported HCT at baseline and an additional 1064 (27%) reported HCT during follow up. Youth experienced 248 seroconversions over 8536 person-years, an incidence rate of 2.91 per 100 person-years [95% confidence interval (CI) 2.56-3.28]. In crude analysis, HCT was not associated with HIV incidence (hazard ratio 1.02, 95% CI 0.79-1.31], but in marginal structural models weighted for risk factors, HCT was protective (hazard ratio 0.59, 95% CI 0.45-0.78).
conclusionIn this high-risk population, after accounting for differences in underlying HIV acquisition risk, HCT was associated with lower HIV incidence. HCT scale-up may have prevention benefits for HIV-uninfected youth.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.