Evidence map›Paper›PMID 23887044›Full record

ArticleAmerican journal of epidemiology2013

Prevalence of diagnosed and undiagnosed type 2 diabetes mellitus among US adolescents: results from the continuous NHANES, 1999-2010.

Ryan T Demmer, Aleksandra M Zuk, Michael Rosenbaum, Moïse Desvarieux

Registry-linked trialAbstract read
In one paragraph

Article in American journal of epidemiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05028205 (Eating Better Together), which is not on this map. Cited by 61 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05028205 narecruitingnot on this mapstarted 2021, after this paper: background citation

Eating Better Together: A Pilot Study

TypeinterventionalSponsorThe University of Tennessee, KnoxvilleRan2021 to 2026Enrolled30ConditionsChildhood Obesity, ObesityArmsPrevention Plus
3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Ryan T Demmer
Aleksandra M Zuk
Michael Rosenbaum
Moïse Desvarieux

Funding

Translational Biomarker Analytical Core (TBAC)P30DK063608 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Anthony W Ferrante · 2003 to 2026
$36.7M
ORAL INFECTIONS, CAROTID ATHEROSCLEROSIS AND STROKER01DE013094 · NIDCR · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI DESVARIEUX, MOISE · 2000 to 2016
$14.4M
Periodontal Infections and Type 2 Diabetes Mellitus RiskR00DE018739 · NIDCR · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI DEMMER, RYAN T. · 2010 to 2014
$783k
NIDCR NIH HHS R00 DE-018739NIDCR NIH HHS R00 DE018739NIDCR NIH HHS R01 DE013094NIDCR NIH HHS R01 DE-13094NIDDK NIH HHS DK 63608NIDDK NIH HHS P30 DK063608
6 · The paper itself

Abstract

Although prevalence and incidence of type 2 diabetes mellitus (T2DM) are reportedly increasing among adolescents, national data are lacking, particularly in regard to undiagnosed T2DM. To estimate the prevalence of diagnosed and undiagnosed T2DM among US adolescents, we analyzed a nationally representative cross-section of 11,888 adolescents aged 12-19 years who received a diabetes interview in the Continuous National Health and Nutrition Examination Survey during 1999-2010. Among them, a random subsample of 4,661 adolescents also had fasting blood samples collected. Persons who reported a previous diabetes diagnosis and were either taking no medication or taking an oral hypoglycemic agent (with or without insulin) were classified as having T2DM; persons who reported using insulin alone were classified as having type 1 diabetes. Undiagnosed diabetes was defined as a fasting plasma glucose concentration of ≥126 mg/dL and was assumed to be type 2. In the fasting subsample, 31 diabetes cases (types 1 and 2) were identified, representing a prevalence of 0.84% (weighted 95% confidence interval (CI): 0.51, 1.40) (276,638 cases; 95% CI: 134,255, 419,020). Estimates of the prevalences of type 1 and type 2 diabetes were 0.48% (95% CI: 0.23, 1.02) and 0.36% (95% CI: 0.20, 0.67), respectively, indicating that T2DM accounted for 43% of all cases. Further, undiagnosed T2DM prevalence was 0.12% (95% CI: 0.05, 0.31), representing 34% of T2DM cases (40,611 cases; 95% CI: 2,850, 78,373). T2DM accounts for approximately half of adolescent diabetes in the United States, and one-third of these cases are undiagnosed.

Indexed as

AdolescentAdultBlood GlucoseChildCross-Sectional StudiesDiabetes Mellitus, Type 1Diabetes Mellitus, Type 2FemaleHumansIncidenceMaleNutrition SurveysPrevalenceSex DistributionSocioeconomic FactorsUnited StatesBlood Glucoseadolescentsdiabetes mellitusetiologyprevalenceundiagnosed diabetes

Identifiers

PMID23887044
PMCPMC3783093

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.