Evidence map›Paper›PMID 23886910›Full record

ReviewMethods (San Diego, Calif.)2013

Single cell spectroscopy: noninvasive measures of small-scale structure and function.

Charilaos Mousoulis, Xin Xu, David A Reiter, Corey P Neu

Open access · greenAbstract readReview
In one paragraph

Review in Methods (San Diego, Calif.), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Charilaos MousoulisWeldon School of Biomedical Engineering, Purdue University, West Lafayette, IN 47907, United States.
Xin Xu
David A Reiter
Corey P Neu
Purdue University West Lafayette · USNational Institute on Aging · US

Funding

Combined Biophysical and Biochemical Study of Single CellsR21AR064178 · NIAMS · PURDUE UNIVERSITY · PI NEU, COREY P · 2012 to 2013
$405k
Intramural NIH HHSNIAMS NIH HHS R21 AR064178
6 · The paper itself

Abstract

The advancement of spectroscopy methods attained through increases in sensitivity, and often with the coupling of complementary techniques, has enabled real-time structure and function measurements of single cells. The purpose of this review is to illustrate, in light of advances, the strengths and the weaknesses of these methods. Included also is an assessment of the impact of the experimental setup and conditions of each method on cellular function and integrity. A particular emphasis is placed on noninvasive and nondestructive techniques for achieving single cell detection, including nuclear magnetic resonance, in addition to physical, optical, and vibrational methods.

Indexed as

HumansMagnetic Resonance SpectroscopyMicroscopy, Atomic ForceMicroscopy, FluorescenceSingle-Cell AnalysisSpectrum Analysis, RamanAtomic force microscopyFluorescence microscopyNuclear magnetic resonanceSingle cellsSpectroscopy

Identifiers

PMID23886910
PMCPMC3833896
OpenAlexW2075626577

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.