ArticleAJNR. American journal of neuroradiology2014
Intramedullary spinal cord metastases: visibility on PET and correlation with MRI features.
Article in AJNR. American journal of neuroradiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Incidence, epidemiology, radiology, and classification of metastatic spine tumors: WFNS Spine Committee recommendations.Neurosurgical review · 2024Pooled it
- Physiological distribution ofThe journal of spinal cord medicine · 2021Pooled it
- Diagnostic Value of Spinal Cord Lesion Metabolism on [European journal of neurology · 2026Article
- It Looks Like a Spinal Cord Tumor but It Is Not.Cancers · 2024Review
- [AJNR. American journal of neuroradiology · 2022Review
- Article
- Potential role ofAsia Oceania journal of nuclear medicine & biology · 2021Article
- Diagnosis of non-osseous spinal metastatic disease: the role of PET/CT and PET/MRI.Journal of neuro-oncology · 2018Review
- Clinical Significance of Incidental FocalNuclear medicine and molecular imaging · 2017Article
- Intramedullary Spinal Cord Metastasis from Breast Cancer Mimicking Delayed Radiation Myelopathy: Detection With (18)F-FDG PET/CT.Nuclear medicine and molecular imaging · 2016Article
- Association betweenJournal of solid tumors · 2016Article
- Intramedullary spinal cord metastases: prognostic value of MRI and clinical features from a 13-year institutional case series.AJNR. American journal of neuroradiology · 2015Article
- Intramedullary spinal cord metastasis from rectal cancer.Annals of coloproctology · 2014Article
- Asymptomatic cauda equina metastasis in a patient with nasopharyngeal carcinoma: Detection by (18)F-FDG PET/CT.Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, India · 2014Article
- Recurrent Renal Carcinoma with Solitary Intramedullary Spinal Cord Metastasis.Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, IndiaArticle
- Diagnostic value ofMedicine internationalArticle
- Unsuspected Intramedullary Spinal Cord Metastasis Detected by FDG PET/CT.Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, IndiaArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeStudies systematically evaluating the detection of intramedullary spinal cord metastasis with PET are lacking. Our purpose was to evaluate the visibility of intramedullary spinal cord metastasis on PET in a single institutional series and to correlate PET and MR imaging features. MATERIALS AND
methodsPatients were included if pretreatment MR imaging identifying an intramedullary spinal cord metastasis and an [(18)F] FDG-PET examination near the time of MR imaging were available. PET examinations were retrospectively reviewed, with reviewers blinded and then unblinded to the PET report and MR imaging findings. PET intramedullary spinal cord metastasis features were compared with and correlated with previously analyzed MR imaging lesion characteristics. Original clinical PET reports were reviewed.
resultsThe final study sample was 10 PET examinations in 10 patients with 13 intramedullary spinal cord metastases. In 7 (70%) patients, retrospective blinded review demonstrated convincing evidence of 10 (77%) intramedullary spinal cord metastases. Three MR imaging features correlated with intramedullary spinal cord metastases being visible on PET compared with those nonvisible, respectively: larger lesion enhancement size: mean size: 32.1 mm versus 6.0 mm (P = .038); larger longitudinal extent of T2 signal abnormality: mean 5.6 versus 1.0 segments (P = .0081); and larger ratio of extent of T2 signal abnormality to contrast enhancement: 3.8 versus 1.0 (P = .0069). Intramedullary spinal cord metastasis was confidently reported clinically in 2 (20%) patients, accounting for 5 (38%) intramedullary spinal cord metastases.
conclusionsMost intramedullary spinal cord metastases can be detected on PET when performed near the time of pretreatment MR imaging. However, intramedullary spinal cord metastases may not be clinically reported on PET. Larger lesions with more edema are more likely to be visible. The spinal cord should be specifically and carefully assessed on PET for evidence of intramedullary spinal cord metastases to provide timely diagnosis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.