Evidence map›Paper›PMID 23886637›Full record

ReviewRespiratory physiology & neurobiology2013

Ventilatory control in infants, children, and adults with bronchopulmonary dysplasia.

Melissa L Bates, De-Ann M Pillers, Mari Palta, Emily T Farrell, Marlowe W Eldridge

Registry-linked trialOpen access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Respiratory physiology & neurobiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00005289 (Risk Factors in Bronchopulmonary Dysplasia), which is not on this map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00005289 completednot on this map

Risk Factors in Bronchopulmonary Dysplasia (Newborn Lung Project)

TypeobservationalSponsorUniversity of Wisconsin, MadisonRan1987 to 2008Enrolled2,202ConditionsBronchopulmonary Dysplasia, Lung Diseases, Respiratory Distress Syndrome
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Perinatal Hypoxemia and Oxygen Sensing.Comprehensive Physiology · 2021
    Article
  6. Article
  7. Review
  8. Acute and chronic changes in the control of breathing in a rat model of bronchopulmonary dysplasia.American journal of physiology. Lung cellular and molecular physiology · 2019
    Article
  9. Cardioventilatory Control in Preterm-born Children and the Risk of Obstructive Sleep Apnea.American journal of respiratory and critical care medicine · 2018
    Article
  10. Review
  11. Respiratory consequences of prematurity: evolution of a diagnosis and development of a comprehensive approach.Journal of perinatology : official journal of the California Perinatal Association · 2015
    Review
  12. Abnormal ventilatory responses in adults born prematurely.The New England journal of medicine · 2014
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Melissa L BatesDepartment of Pediatrics, Division of Critical Care, University of Wisconsin, Madison, WI, USA; John Rankin Laboratory of Pulmonary Medicine, University of Wisconsin, Madison, WI, USA. Electronic address: mlbates@pediatrics.wisc.edu.
De-Ann M Pillers
Mari Palta
Emily T Farrell
Marlowe W Eldridge
University of Wisconsin–Madison · US

Funding

Respiratory NeurobiologyT32HL007654 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI MITCHELL, GORDON S. · 1987 to 2011
$4.0M
Right Heart-Pulmonary Vascular Interactions in Bronchopulmonary DysplasiaR01HL115061 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI ELDRIDGE, MARLOWE · 2012 to 2016
$3.2M
Comprehensive Characterization of Intrapulmonary Arteriovenous Pathways in HealthR01HL086897 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI ELDRIDGE, MARLOWE · 2008 to 2012
$1.8M
NHLBI NIH HHS 5R01HL086897NHLBI NIH HHS 5T32HL007654NHLBI NIH HHS R01 HL086897NHLBI NIH HHS R01 HL115061NHLBI NIH HHS T32 HL007654
6 · The paper itself

Abstract

Bronchopulmonary dysplasia (BPD), or chronic lung disease of prematurity, occurs in ~30% of preterm infants (15,000 per year) and is associated with a clinical history of mechanical ventilation and/or high inspired oxygen at birth. Here, we describe changes in ventilatory control that exist in patients with BPD, including alterations in chemoreceptor function, respiratory muscle function, and suprapontine control. Because dysfunction in ventilatory control frequently revealed when O2 supply and CO2 elimination are challenged, we provide this information in the context of four important metabolic stressors: stresses: exercise, sleep, hypoxia, and lung disease, with a primary focus on studies of human infants, children, and adults. As a secondary goal, we also identify three key areas of future research and describe the benefits and challenges of longitudinal human studies using well-defined patient cohorts.

Indexed as

AdultBronchopulmonary DysplasiaChildExerciseHumansHypoxiaInfantPulmonary VentilationRespiration, ArtificialSleepVentilator-Induced Lung InjuryBronchopulmonary dysplasiaExerciseHypoxiaPremature infantSleepVentilatory control

Identifiers

PMID23886637
PMCPMC3812402
OpenAlexW2045511518

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.